Hydrochloric Acid → (3aRS,4RS,5RS,7aRS)-7,7-diphenyl-4-(2-methoxyphenyl)-2-(2-methoxyphenyl)-acetylperhydroisoindole-4,5-diol

HRID 87509

Reaction equation

HRID 87509 reaction equation
[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:40][O:41][c:42]1[c:43]([CH2:48][C:49](=[O:50])[OH:51])[cH:44][cH:45][cH:46][cH:47]1.[Cl:52][CH2:53][Cl:54].[ClH:1].[c:2]1([C:8]2([c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[CH2:9][CH:10]([OH:26])[C:11]([OH:17])([c:18]3[c:19]([O:24][CH3:25])[cH:20][cH:21][cH:22][cH:23]3)[CH:12]3[CH2:13][NH:14][CH2:15][CH:16]23)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([C:8]2([c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[CH2:9][CH:10]([OH:26])[C:11]([OH:17])([c:18]3[c:19]([O:24][CH3:25])[cH:20][cH:21][cH:22][cH:23]3)[CH:12]3[CH2:13][NH:14][CH:15]([C:49]([CH2:48][c:43]4[c:42]([O:41][CH3:40])[cH:47][cH:46][cH:45][cH:44]4)=[O:50])[CH:16]23)[cH:3][cH:4][cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 71342-Methoxyphenylacetic acidHCID 8471TriethylamineHCID 19047650(3aRS,4RS,5RS,7aRS)-7,7-diphenyl-4-(2-methoxyphenyl)perhydro-4,5-isoindolediol

Product 1

HCID 67719041(3aRS,4RS,5RS,7aRS)-7,7-diphenyl-4-(2-methoxyphenyl)-2-(2-methoxyphenyl)-acetylperhydroisoindole-4,5-diol

Sources & evidence

ORD record
ord-e8dfce918b79486193ba4547e7027ac2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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