Pyridine → tert-Butyl 2-[3-chloro-4-(3-oxomorpholin-4-yl)phenylcarbamoyl]pyrazolidine-1-carboxylate

HRID 88476

Reaction equation

HRID 88476 reaction equation
[CH2:47]([N:48]([CH:49]([CH3:50])[CH3:51])[CH:52]([CH3:53])[CH3:54])[CH3:55].[Cl:16][C:17](=[O:18])[O:19][c:20]1[cH:21][cH:22][c:23]([N+:24]([O-:25])=[O:26])[cH:27][cH:28]1.[Cl:56][CH2:57][Cl:58].[N:35]1([C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[NH:36][CH2:37][CH2:38][CH2:39]1.[NH2:1][c:2]1[cH:3][c:4]([Cl:15])[c:5]([N:8]2[C:9](=[O:14])[CH2:10][O:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[cH:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1>>[NH:1]([c:2]1[cH:3][c:4]([Cl:15])[c:5]([N:8]2[C:9](=[O:14])[CH2:10][O:11][CH2:12][CH2:13]2)[cH:6][cH:7]1)[C:17](=[O:18])[N:36]1[N:35]([C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[CH2:39][CH2:38][CH2:37]1

Participants

7

Reactant 6

HCID 1049PyridineHCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 821294-Nitrophenyl chloroformateHCID 21857793tert-Butyl pyrazolidine-1-carboxylateHCID 231053274-(4-Amino-2-chlorophenyl)morpholin-3-one

Product 1

HCID 86607077tert-Butyl 2-[3-chloro-4-(3-oxomorpholin-4-yl)phenylcarbamoyl]pyrazolidine-1-carboxylate

Sources & evidence

ORD record
ord-d05fcf63430e41399587405176de18c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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