Acetate → 1-(3-Methoxyphenyl)piperidine

Reaction equation

[Br:7][c:8]1[cH:9][c:10]([O:14][CH3:15])[cH:11][cH:12][cH:13]1.[C:24]([O-:25])(=[O:26])[CH3:27].[C:29]([O-:30])(=[O:31])[CH3:32].[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[CH3:16][c:17]1[c:18]([CH3:19])[cH:20][cH:21][cH:22][cH:23]1.[Pd+2:28]>>[CH2:1]1[CH2:2][CH2:3][N:4]([c:8]2[cH:9][c:10]([O:14][CH3:15])[cH:11][cH:12][cH:13]2)[CH2:5][CH2:6]1

Participants

Reactant 5

HCID 175Acetate2×

HCID 7237O-Xylene

HCID 8082Piperidine

HCID 169713-Bromoanisole

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 6057251-(3-Methoxyphenyl)piperidine

Sources & evidence

ORD record: ord-f7450fc5f4434fe2843e984aec96682f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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