Trimethyl orthoformate → 3-Ethylenedioxy-11beta-fluoro-7alpha-methylestr-5(10)-en-17beta-ol

Reaction equation

[CH:1]([O:6][CH3:7])(OC)OC.O.[C:9]1(C)C=CC(S(O)(=O)=O)=CC=1.[F:20][C@H:21]1[CH2:38][C@@:36]2([CH3:37])[C@@H:32]([CH2:33][CH2:34][C@@H:35]2[OH:39])[C@H:31]2[C@H:22]1[C@@H:23]1[C:28]([CH2:29][C@H:30]2[CH3:40])=[CH:27][C:26](=[O:41])C[CH2:24]1.C(=O)([O-])[O-].[Na+].[Na+]>ClCCl.C(OCC)(=O)C.C(O)CO>[CH2:9]1[CH2:7][O:6][CH:1]2[CH:26]([CH2:27][C:28]3[CH2:29][C@@H:30]([CH3:40])[C@@H:31]4[C@@H:22]([C:23]=3[CH2:24]2)[C@@H:21]([F:20])[CH2:38][C@@:36]2([CH3:37])[C@H:32]4[CH2:33][CH2:34][C@@H:35]2[OH:39])[O:41]1