Sodium hydride → 2-{5-Phenyl-4-[(pyridin-2-ylmethyl)amino]thieno[2,3-d]pyrimidin-2-yl}malonic acid diethyl ester
Reaction equation
[H-].[Na+].[CH2:3]([O:5][C:6](=[O:31])[CH2:7][C:8]1[N:9]=[C:10]([NH:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=2)[C:11]2[C:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:15][S:14][C:12]=2[N:13]=1)[CH3:4]>C(=O)(OCC)OCC>[CH2:3]([O:5][C:6](=[O:31])[CH:7]([C:8]1[N:9]=[C:10]([NH:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=2)[C:11]2[C:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:15][S:14][C:12]=2[N:13]=1)[C:6]([O:5][CH2:3][CH3:4])=[O:31])[CH3:4]Participants
4
