Olprinone → 2-Chloro-5-(imidazo[1,2-a]pyridin-6-yl)-6-methylpyridine-3-carbonitrile

HRID 92371

Reaction equation

HRID 92371 reaction equation
[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[P:20]([Cl:21])([Cl:22])([Cl:23])=[O:24].[n:1]1[cH:2][cH:3][n:4]2[c:5]1[cH:6][cH:7][c:8](-[c:10]1[cH:11][c:12]([C:18]#[N:19])[c:13](=[O:17])[nH:14][c:15]1[CH3:16])[cH:9]2>>[n:1]1[cH:2][cH:3][n:4]2[c:5]1[cH:6][cH:7][c:8](-[c:10]1[cH:11][c:12]([C:18]#[N:19])[c:13]([Cl:22])[n:14][c:15]1[CH3:16])[cH:9]2

Participants

4

Reactant 3

HCID 4593OlprinoneHCID 6228DimethylformamideHCID 24813Phosphorus oxychloride

Product 1

HCID 138523142-Chloro-5-(imidazo[1,2-a]pyridin-6-yl)-6-methylpyridine-3-carbonitrile

Sources & evidence

ORD record
ord-dee7ac61847f4182879b41a0ab77b31a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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