Dimethyl Sulfoxide → 4-(Pyridin-2-ylaminomethyl)-benzaldehyde

HRID 933242

Reaction equation

HRID 933242 reaction equation
[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[CH3:7][S:8]([CH3:9])=[O:10].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:34][CH2:35][Cl:36].[n:11]1[c:12]([NH:17][CH2:18][c:19]2[cH:20][cH:21][c:22]([CH2:25][OH:26])[cH:23][cH:24]2)[cH:13][cH:14][cH:15][cH:16]1>>[n:11]1[c:12]([NH:17][CH2:18][c:19]2[cH:20][cH:21][c:22]([CH:25]=[O:26])[cH:23][cH:24]2)[cH:13][cH:14][cH:15][cH:16]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 22018543(4-((Pyridin-2-ylamino)methyl)phenyl)methanol

Product 1

HCID 220187754-(Pyridin-2-ylaminomethyl)-benzaldehyde

Sources & evidence

ORD record
ord-ae8dde2c87a14e8fa6dac4c80eca2b31
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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