4,7-Dichloroquinoline → 7-Chloro-4-(4-fluorophenoxy)quinoline
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([Cl:12])[cH:9][cH:10][c:11]12.[F:13][c:14]1[cH:15][cH:16][c:17]([OH:20])[cH:18][cH:19]1.[c:21]1([CH3:22])[c:23]([CH3:24])[cH:25][cH:26][cH:27][cH:28]1>>[c:2]1([O:20][c:17]2[cH:16][cH:15][c:14]([F:13])[cH:19][cH:18]2)[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([Cl:12])[cH:9][cH:10][c:11]12Participants
4
Sources & evidence
- ORD record
- ord-9aeb38e1302c40cebb17af5fc6a24c38
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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