Sodium ion → 5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[1-(cyclopropylmethoxy)butan-2-yl]-3-prop-2-enylpiperidin-2-one

HRID 93772

Reaction equation

HRID 93772 reaction equation
[Br:32][CH2:33][CH:34]1[CH2:35][CH2:36]1.[CH2:1]([CH:2]=[CH2:3])[CH:4]1[C:5](=[O:29])[N:6]([CH:24]([CH2:25][OH:26])[CH2:27][CH3:28])[CH:7]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:8]([c:10]2[cH:11][c:12]([Cl:16])[cH:13][cH:14][cH:15]2)[CH2:9]1.[H-:30].[Na+:31].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41]>>[CH2:1]([CH:2]=[CH2:3])[CH:4]1[C:5](=[O:29])[N:6]([CH:24]([CH2:25][O:26][CH2:33][CH:34]2[CH2:35][CH2:36]2)[CH2:27][CH3:28])[CH:7]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:8]([c:10]2[cH:11][c:12]([Cl:16])[cH:13][cH:14][cH:15]2)[CH2:9]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 81503BromomethylcyclopropaneHCID 166653HydrideHCID 768347065-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-(1-hydroxybutan-2-yl)-3-prop-2-enylpiperidin-2-one

Product 1

HCID 768347165-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[1-(cyclopropylmethoxy)butan-2-yl]-3-prop-2-enylpiperidin-2-one

Sources & evidence

ORD record
ord-b6400a87d8c247c7b84205086e02c2b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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