Hydrochloric Acid → 6-chloro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid

HRID 937897

Reaction equation

HRID 937897 reaction equation
[CH3:18][OH:19].[CH3:3][O:4][C:5](=[O:6])[c:7]1[c:8]2[c:9]([n:10][c:11]([Cl:13])[cH:12]1)[nH:14][cH:15][cH:16]2.[ClH:17].[Li+:1].[OH-:2]>>[O:4]=[C:5]([OH:6])[c:7]1[c:8]2[c:9]([n:10][c:11]([Cl:13])[cH:12]1)[nH:14][cH:15][cH:16]2

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 961HydroxideHCID 28486Lithium ionHCID 53413062Methyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-4-carboxylate

Product 1

HCID 533995756-chloro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid

Sources & evidence

ORD record
ord-ed02227af47548edb320a884e22209a9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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