Sodium ion → 5-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-1-(4-hydroxymethyl-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one

HRID 939249

Reaction equation

HRID 939249 reaction equation
[BH4-:43].[CH2:35]([O:36][C:37]([Cl:38])=[O:39])[CH:40]([CH3:41])[CH3:42].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9](-[c:27]3[c:28]([Cl:34])[cH:29][c:30]([Cl:33])[cH:31][cH:32]3)[n:10][c:11]3[c:12]([c:13]2=[O:14])[cH:15][n:16][n:17]3-[c:18]2[cH:19][cH:20][c:21]([C:22](=[O:23])[OH:24])[cH:25][cH:26]2)[cH:6][cH:7]1.[Na+:44].[OH2:50]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9](-[c:27]3[c:28]([Cl:34])[cH:29][c:30]([Cl:33])[cH:31][cH:32]3)[n:10][c:11]3[c:12]([c:13]2=[O:14])[cH:15][n:16][n:17]3-[c:18]2[cH:19][cH:20][c:21]([CH2:22][OH:23])[cH:25][cH:26]2)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 62365Isobutyl chloroformateHCID 578980584-[5-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-4-oxo-4,5-dihydro-pyrazolo[3,4-d]pyrimidin-1-yl]-benzoic acid

Product 1

HCID 578979015-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-1-(4-hydroxymethyl-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one

Sources & evidence

ORD record
ord-e65e0f99933545679b44d830e15a8408
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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