Acetonitrile → (5-Bromo-2-chloropyrimidin-4-yl)isopropylamine
Reaction equation
[Br:12][c:13]1[c:14]([Cl:20])[n:15][c:16]([Cl:19])[n:17][cH:18]1.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:21][C:22]#[N:23].[NH2:8][CH:9]([CH3:10])[CH3:11]>>[NH:8]([CH:9]([CH3:10])[CH3:11])[c:14]1[c:13]([Br:12])[cH:18][n:17][c:16]([Cl:19])[n:15]1Participants
5
Sources & evidence
- ORD record
- ord-7cc67b23fb334590aa07d267f7bec9d5
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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