Ethyl Acetate → 4-(4-Methyl-piperidin-1-yl)-benzonitrile
Reaction equation
[CH3:10][CH:11]1[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1.[CH3:17][CH2:18][O:19][C:20](=[O:21])[CH3:22].[F:1][c:2]1[cH:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1>>[c:2]1([N:14]2[CH2:13][CH2:12][CH:11]([CH3:10])[CH2:16][CH2:15]2)[cH:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1Participants
4
Sources & evidence
- ORD record
- ord-352566aaaacc4096bca167ae0309368c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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