Tetrahydrofuran → 4-(2-Hydroxy-ethyl)-5-thiophen-2-yl-2,4-dihydro-[1,2,4]triazole-3-thione

HRID 942079

Reaction equation

HRID 942079 reaction equation
[Al+3:2].[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[s:7]1[c:8](-[c:12]2[n:13][nH:14][c:15](=[S:21])[n:16]2[CH2:17][C:18](=[O:19])[OH:20])[cH:9][cH:10][cH:11]1>>[s:7]1[c:8](-[c:12]2[n:13][nH:14][c:15](=[S:21])[n:16]2[CH2:17][CH2:18][OH:19])[cH:9][cH:10][cH:11]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 49625532-[3-sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]acetic acid

Product 1

HCID 859371364-(2-Hydroxy-ethyl)-5-thiophen-2-yl-2,4-dihydro-[1,2,4]triazole-3-thione

Sources & evidence

ORD record
ord-3828bf1dee444db4ab8f648a1e8c7940
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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