Dichloromethane → 2-bromo-N-(6-chloro-2-phenylpyrimidin-4-yl)acetamide

HRID 943393

Reaction equation

HRID 943393 reaction equation
[Br:15][CH2:16][C:17](=[O:18])[Br:19].[CH:20]([N:21]([CH2:22][CH3:23])[CH:24]([CH3:25])[CH3:26])([CH3:27])[CH3:28].[Cl:1][c:2]1[cH:3][c:4]([NH2:14])[n:5][c:6](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:7]1.[Cl:29][CH2:30][Cl:31]>>[Cl:1][c:2]1[cH:3][c:4]([NH:14][C:17]([CH2:16][Br:15])=[O:18])[n:5][c:6](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 61147Bromoacetyl bromideHCID 81531DiisopropylethylamineHCID 3177476-Chloro-2-phenylpyrimidin-4-amine

Product 1

HCID 223791512-bromo-N-(6-chloro-2-phenylpyrimidin-4-yl)acetamide

Sources & evidence

ORD record
ord-43e8cb6bbe70449780504fb3c9c1c9b8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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