Chloride → 2-Methyl-5-(2,2,2-trifluoroethoxy)pyridine

HRID 943976

Reaction equation

HRID 943976 reaction equation
[Br:15][CH2:16][C:17]([F:18])([F:19])[F:20].[C:9](=[O:10])([O-:11])[O-:12].[Cl-:26].[K+:13].[K+:14].[Na+:27].[O:21]=[CH:22][N:23]([CH3:24])[CH3:25].[OH:1][c:2]1[cH:3][cH:4][c:5]([CH3:8])[n:6][cH:7]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([CH3:8])[n:6][cH:7]1)[CH2:16][C:17]([F:18])([F:19])[F:20]

Participants

8

Reactant 7

HCID 312ChlorideHCID 813Potassium Cation2×HCID 923Sodium ionHCID 6228DimethylformamideHCID 142752-Methyl-5-hydroxypyridineHCID 19660Carbonate IonHCID 678982-Bromo-1,1,1-trifluoroethane

Product 1

HCID 235684332-Methyl-5-(2,2,2-trifluoroethoxy)pyridine

Sources & evidence

ORD record
ord-1158137c262c412a9f941c16a66d2faf
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

Loading…