Tetrahydrofuran → 7-fluoro-3,4-dihydro-2H-1,4-benzoxazine
Reaction equation
[Al+3:14].[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[H-:13].[H-:16].[H-:17].[H-:18].[Li+:15].[O:1]=[C:2]1[NH:3][c:4]2[c:5]([cH:8][c:9]([F:12])[cH:10][cH:11]2)[O:6][CH2:7]1>>[CH2:2]1[NH:3][c:4]2[c:5]([cH:8][c:9]([F:12])[cH:10][cH:11]2)[O:6][CH2:7]1Participants
6
Sources & evidence
- ORD record
- ord-4ebdfffa980e49c5989fbf2a8cd4a561
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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