Acetate → 5-Phenoxy-1,2,3,4-tetrahydroquinoline

HRID 949754

Reaction equation

HRID 949754 reaction equation
[C:31]([O-:32])(=[O:33])[CH3:34].[C:36]([O-:37])(=[O:38])[CH3:39].[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[Cl:28][CH2:29][Cl:30].[Cu+2:35].[NH:1]1[CH2:2][CH2:3][CH2:4][c:5]2[c:6]([OH:11])[cH:7][cH:8][cH:9][c:10]21.[OH:12][B:13]([OH:14])[c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1>>[NH:1]1[CH2:2][CH2:3][CH2:4][c:5]2[c:6]([O:11][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)[cH:7][cH:8][cH:9][c:10]21

Participants

7

Reactant 6

HCID 175Acetate2×HCID 6344DichloromethaneHCID 8471TriethylamineHCID 27099Cupric cationHCID 66827Phenylboronic AcidHCID 30460361,2,3,4-Tetrahydroquinolin-5-ol

Product 1

HCID 4875475-Phenoxy-1,2,3,4-tetrahydroquinoline

Sources & evidence

ORD record
ord-9b255ca4ea6e4ff2b4b42aaee985f640
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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