Hydrochloric Acid → Tert-butyl 5-amino-2-chloropyridin-3-ylcarbamate

HRID 950795

Reaction equation

HRID 950795 reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([N:16]=[C:17]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:6][c:7]1[NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15].[ClH:30]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([NH2:16])[cH:6][c:7]1[NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 86647087Tert-butyl 2-chloro-5-(diphenylmethyleneamino)pyridin-3-ylcarbamate

Product 1

HCID 86647086Tert-butyl 5-amino-2-chloropyridin-3-ylcarbamate

Sources & evidence

ORD record
ord-7c8e9fa0fd0843caaa9d8e734ed73ccb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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