Acetate → 2-NITRO-4-TRIFLUOROMETHYL-BIPHENYL

HRID 951113

Reaction equation

HRID 951113 reaction equation
[Br:1][c:2]1[c:3]([N+:12](=[O:13])[O-:14])[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1.[C:65]([O-:66])(=[O:67])[CH3:68].[C:70]([O-:71])(=[O:72])[CH3:73].[CH3:74][c:75]1[cH:76][cH:77][cH:78][cH:79][cH:80]1.[OH:15][B:16]([OH:17])[c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[Pd+2:69].[Pd:24]([Cl:25])[Cl:26].[c:27]1([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:41][cH:42][cH:43][cH:44][cH:45]1.[c:46]1([P:47]([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[cH:60][cH:61][cH:62][cH:63][cH:64]1>>[c:2]1(-[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:3]([N+:12](=[O:13])[O-:14])[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 1140TolueneHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 66827Phenylboronic AcidHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 5207064-Bromo-3-nitrobenzotrifluoride

Product 1

HCID 113001192-NITRO-4-TRIFLUOROMETHYL-BIPHENYL

Sources & evidence

ORD record
ord-ae0e135717224940a0d6bcb4918f9ea4
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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