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Tetrahydrofuran → 2-Cyclohexylaminothiazol-4-ylmethanol

HRID 955813
Notes
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Reaction equation

HRID 955813 reaction equation
[Al+3:19].[CH:1]1([NH:7][c:8]2[s:9][cH:10][c:11]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[n:12]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[H-:18].[H-:21].[H-:22].[H-:23].[Li+:20].[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1>>[CH:1]1([NH:7][c:8]2[s:9][cH:10][c:11]([CH2:13][OH:14])[n:12]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1
ParticipantsSources & evidenceReaction notes

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 15053542Ethyl 2-(cyclohexylamino)-1,3-thiazole-4-carboxylate

Product 1

HCID 150535602-Cyclohexylaminothiazol-4-ylmethanol

Sources & evidence

ORD record
ord-073670e77edb4a0cb807cbb4179ea7cb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes