Tetrahydrofuran → 5-chloro-2-methoxy-N-[3-[2-(2-methoxyethoxy)ethyl]-5-methyl-1,3-thiazol-2-ylidene]benzamide

HRID 959808

Reaction equation

HRID 959808 reaction equation
[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:29][O:30][CH2:31][CH2:32][O:33][CH2:34][CH2:35][n:36]1[c:37](=[NH:42])[s:38][c:39]([CH3:41])[cH:40]1.[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[Cl:13][c:14]1[cH:15][cH:16][c:17]([O:18][CH3:19])[c:20]([C:22]([Cl:23])=[O:24])[cH:21]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:11][CH3:12])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[S:25]([Cl:26])([Cl:27])=[O:28]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:11][CH3:12])[c:6]([C:7](=[O:9])[N:42]=[c:37]2[n:36]([CH2:35][CH2:34][O:33][CH2:32][CH2:31][O:30][CH3:29])[cH:40][c:39]([CH3:41])[s:38]2)[cH:10]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 24386Thionyl ChlorideHCID 769705-Chloro-o-anisic acidHCID 123841765-Chloro-2-methoxybenzoyl chlorideHCID 668587283-(2-(2-methoxyethoxy)ethyl)-5-methylthiazol-2(3H)-imine

Product 1

HCID 248982715-chloro-2-methoxy-N-[3-[2-(2-methoxyethoxy)ethyl]-5-methyl-1,3-thiazol-2-ylidene]benzamide

Sources & evidence

ORD record
ord-61295eb7aca34ff2907cb052760cd644
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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