→ Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

HRID 962305

Reaction equation

HRID 962305 reaction equation
CC(=O)O.CCO.CCOC(=O)CC(C)=O.NC(N)=S.O.O.O.O.O.O.O.O=Cc1ccccc1.[Cl-].[Cl-].[Cl-].[La+3]>>CCOC(=O)C1=C(C)NC(=S)NC1c1ccccc1

Participants

7

Reactant 0

No Reactant data yet.

Product 1

HCID 2737412Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylateYield 56%

Reagents, catalysts & solvents 6

HCID 176Acetic AcidOtherHCID 240BenzaldehydeOtherHCID 702EthanolOtherHCID 8868Ethyl AcetoacetateOtherHCID 165791Lanthanum chloride heptahydrateOtherHCID 2723790ThioureaOther

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. filtrationKeep solid
  3. washNo procedure recorded
  4. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-1a56249fabae404aad550d864f59e8a1
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Linked notes

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