→ Ethyl 1,6-dimethyl-4-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate

HRID 962306

Reaction equation

HRID 962306 reaction equation
CCO.CCOC(=O)CC(C)=O.CNC(N)=S.O.O.O.O.O.O.O.O=Cc1ccccc1.[Cl-].[Cl-].[Cl-].[La+3]>>CCOC(=O)C1=C(C)N(C)C(=S)NC1c1ccccc1

Participants

6

Reactant 0

No Reactant data yet.

Product 1

HCID 2784297Ethyl 1,6-dimethyl-4-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylateYield 41%

Reagents, catalysts & solvents 5

HCID 240BenzaldehydeOtherHCID 702EthanolOther2×HCID 8868Ethyl AcetoacetateOtherHCID 165791Lanthanum chloride heptahydrateOtherHCID 2723704MethylthioureaOther

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. filtrationKeep solid
  3. washNo procedure recorded
  4. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-2e902995602a40b69e436eb752ef5f50
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Linked notes

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