→ (+-)-Monastrol

HRID 962308

Reaction equation

HRID 962308 reaction equation
CCO.CCOC(=O)CC(C)=O.NC(N)=S.O.O=Cc1cccc(O)c1.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3]>>CCOC(=O)C1=C(C)NC(=S)NC1c1cccc(O)c1

Participants

6

Reactant 0

No Reactant data yet.

Product 1

HCID 2987927(+-)-MonastrolYield 45%

Reagents, catalysts & solvents 5

HCID 1013-HydroxybenzaldehydeOtherHCID 702EthanolOther2×HCID 8868Ethyl AcetoacetateOtherHCID 2723790ThioureaOtherHCID 45075687Ytterbium(3+) trifluoromethanesulfonate--water (1/3/1)Other

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. additionNo procedure recorded
  3. waitNo procedure recorded
  4. filtrationKeep solid
  5. washNo procedure recorded
  6. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-5f2eb9eec34a4b34a64b274eae68c684
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Linked notes

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