HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

→ Ethyl 6-methyl-2-oxo-4-[2-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

HRID 962312
Notes
Print preview

Reaction equation

HRID 962312 reaction equation
CC(=O)O.CCO.CCOC(=O)CC(C)=O.NC(N)=O.O.O=Cc1ccccc1C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3]>>CCOC(=O)C1=C(C)NC(=O)NC1c1ccccc1C(F)(F)F
ParticipantsConditionsWorkupSources & evidenceReaction notes

Participants

7

Reactant 0

No Reactant data yet.

Product 1

HCID 402867Ethyl 6-methyl-2-oxo-4-[2-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro-5-pyrimidinecarboxylateYield 49%

Reagents, catalysts & solvents 6

HCID 176Acetic AcidOtherHCID 702EthanolOtherHCID 1176UreaOtherHCID 8868Ethyl AcetoacetateOtherHCID 123067o-(Trifluoromethyl)benzaldehydeOtherHCID 45075687Ytterbium(3+) trifluoromethanesulfonate--water (1/3/1)Other

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. filtrationKeep solid
  3. washNo procedure recorded
  4. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-ed3dac19233f4bb188d8174630ab6cd4
Source dataset
Microwave-assisted Biginelli Condensation Dataset
DOI
10.1021/cc010044j
Original link
View source

Reaction notes

Loading…

On this pageParticipantsConditionsWorkupSources & evidenceReaction notes