→ Propan-2-yl 4-methyl-6-(3-nitrophenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate

HRID 962329

Reaction equation

HRID 962329 reaction equation
C=CCNC(N)=O.CC(=O)CC(=O)OC(C)C.CC(=O)O.CCO.O.O=Cc1cccc([N+](=O)[O-])c1.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3]>>C=CCN1C(=O)NC(c2cccc([N+](=O)[O-])c2)C(C(=O)OC(C)C)=C1C

Participants

7

Reactant 0

No Reactant data yet.

Product 1

HCID 11164240Propan-2-yl 4-methyl-6-(3-nitrophenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylateYield 34%

Reagents, catalysts & solvents 6

HCID 176Acetic AcidOtherHCID 702EthanolOtherHCID 74493-NitrobenzaldehydeOtherHCID 11181AllylureaOtherHCID 68329Isopropyl acetoacetateOtherHCID 45075687Ytterbium(3+) trifluoromethanesulfonate--water (1/3/1)Other

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. additionNo procedure recorded
  3. waitNo procedure recorded
  4. filtrationKeep solid
  5. washNo procedure recorded
  6. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-3d92d2f1d1a54a619c20a6194f5f3561
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Linked notes

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