→ 6-Methyl-5-nitro-4-phenyl-3,4-dihydro-1H-pyrimidin-2-one

HRID 962349Notes

Reaction equation

HRID 962349 reaction equation
CC(=O)O.CC(=O)[N+](=O)[O-].CCO.NC(N)=O.O.O.O.O.O.O.O.O=Cc1ccccc1.[Cl-].[Cl-].[Cl-].[La+3]>>CC1=C([N+](=O)[O-])C(c2ccccc2)NC(=O)N1

Participants

7

Reactant 0

No Reactant data yet.

Product 1

HCID 27517056-Methyl-5-nitro-4-phenyl-3,4-dihydro-1H-pyrimidin-2-oneYield 83%

Reagents, catalysts & solvents 6

HCID 176Acetic AcidOtherHCID 240BenzaldehydeOtherHCID 702EthanolOtherHCID 1176UreaOtherHCID 165791Lanthanum chloride heptahydrateOtherHCID 19860303a-NitroacetaldehydeOther

Conditions

Temperature
100 °C

Workup

  1. waitNo procedure recorded
  2. filtrationKeep solid
  3. washNo procedure recorded
  4. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-6e0fd9cca1014e9c8e9f59d3ebf4339e
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Reaction notes

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