Potassium Cation → Tert-butyl 4-cyano-5-(methylthio)thiophene-2-carboxylate

HRID 96746

Reaction equation

HRID 96746 reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[Br:17].[C:18](=[O:19])([O-:20])[O-:21].[C:1](#[N:2])[c:3]1[cH:4][c:5]([C:10](=[O:11])[OH:12])[s:6][c:7]1[S:8][CH3:9].[CH3:24][C:25]([N:26]([CH3:27])[CH3:28])=[O:29].[K+:22].[K+:23]>>[C:1](#[N:2])[c:3]1[cH:4][c:5]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[s:6][c:7]1[S:8][CH3:9]

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 10485t-Butyl bromideHCID 19660Carbonate IonHCID 31374DimethylacetamideHCID 455943124-Cyano-5-methylsulfanylthiophene-2-carboxylic acid

Product 1

HCID 66785900Tert-butyl 4-cyano-5-(methylthio)thiophene-2-carboxylate

Sources & evidence

ORD record
ord-89fa4054a68e4d37ab06bcdeabdb3b62
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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