Hydrochloric Acid → Racemic 4-(2-formyl-4-iodo-phenoxy)-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH:20]2[O:21][CH:22]2[CH2:23][CH2:24]1.[ClH:25].[K:31].[O:26]=[CH:27][N:28]([CH3:29])[CH3:30].[OH:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][c:7]([I:10])[cH:8][cH:9]1>>[O:1]([c:2]1[c:3]([CH:4]=[O:5])[cH:6][c:7]([I:10])[cH:8][cH:9]1)[CH:22]1[CH:20]([OH:21])[CH2:19][N:18]([C:16]([O:15][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:17])[CH2:24][CH2:23]1Participants
6
Sources & evidence
- ORD record
- ord-c7ff18ce31fa41d0aa912cbc3a2ff345
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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