Dimethylformamide → N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide

HRID 98256

Reaction equation

HRID 98256 reaction equation
[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[Cl:11][CH2:12][Cl:13].[Cl:14][c:15]1[cH:16][c:17]2[c:22]([c:23]([Cl:25])[cH:24]1)[CH2:21][N:20]([CH3:26])[CH2:19][CH:18]2[c:27]1[cH:28][c:29]([S:33](=[O:34])(=[O:35])[Cl:36])[cH:30][cH:31][cH:32]1.[NH2:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][NH2:10].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41]>>[NH2:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][NH:10][S:33]([c:29]1[cH:28][c:27]([CH:18]2[c:17]3[cH:16][c:15]([Cl:14])[cH:24][c:23]([Cl:25])[c:22]3[CH2:21][N:20]([CH3:26])[CH2:19]2)[cH:32][cH:31][cH:30]1)(=[O:34])=[O:35]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 70248Bis-AminoethylglycolHCID 866723303-(6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzene-1-sulfonyl chloride

Product 1

HCID 67458027N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide

Sources & evidence

ORD record
ord-72fd26b7418347918ae5f2f93be62236
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

Loading…