proline dl-form → 1'-{[5-(methylsulfonyl)-2-furyl]methyl}spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)one

HRID 98881

Reaction equation

HRID 98881 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:7][N:8]2[C:9](=[O:28])[C:10]3([CH2:11][O:12][c:13]4[c:14]3[cH:15][c:16]3[c:17]([cH:21]4)[O:18][CH2:19][O:20]3)[c:22]3[cH:23][cH:24][cH:25][cH:26][c:27]32)[o:6]1.[CH3:29][S:30](=[O:31])[O-:32].[CH3:44][S:45](=[O:46])[CH3:47].[Cu:42][I:43].[Na+:33].[OH:34][C:35]([CH:36]1[NH:37][CH2:38][CH2:39][CH2:40]1)=[O:41]>>[c:2]1([S:30]([CH3:29])(=[O:31])=[O:32])[cH:3][cH:4][c:5]([CH2:7][N:8]2[C:9](=[O:28])[C:10]3([CH2:11][O:12][c:13]4[c:14]3[cH:15][c:16]3[c:17]([cH:21]4)[O:18][CH2:19][O:20]3)[c:22]3[cH:23][cH:24][cH:25][cH:26][c:27]32)[o:6]1

Participants

7

Reactant 6

HCID 614proline dl-formHCID 679Dimethyl SulfoxideHCID 923Sodium ionHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 3870744MethanesulfinateHCID 592634371'-[(5-bromo-2-furyl)methyl]spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

Product 1

HCID 592634181'-{[5-(methylsulfonyl)-2-furyl]methyl}spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)one

Sources & evidence

ORD record
ord-cc804306f41f4b35a991a343343722a0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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