Sodium ion → Ethyl 2-acetyl-4-[4-(4-fluorobenzoyl)piperidino]-butyrate

HRID 99392

Reaction equation

HRID 99392 reaction equation
[C:1]([CH2:2][C:3](=[O:4])[CH3:5])(=[O:6])[O:7][CH2:8][CH3:9].[Cl:14][CH2:15][CH2:16][N:17]1[CH2:18][CH2:19][CH:20]([C:23]([c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)=[O:31])[CH2:21][CH2:22]1.[H-:10].[I-:13].[Na+:11].[Na+:12].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[C:1]([CH:2]([C:3](=[O:4])[CH3:5])[CH2:15][CH2:16][N:17]1[CH2:18][CH2:19][CH:20]([C:23]([c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)=[O:31])[CH2:21][CH2:22]1)(=[O:6])[O:7][CH2:8][CH3:9]

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 8028TetrahydrofuranHCID 8868Ethyl AcetoacetateHCID 30165Iodide IonHCID 166653HydrideHCID 10516150Methanone, [1-(2-chloroethyl)-4-piperidinyl](4-fluorophenyl)-

Product 1

HCID 14882705Ethyl 2-acetyl-4-[4-(4-fluorobenzoyl)piperidino]-butyrate

Sources & evidence

ORD record
ord-d7e730d354354b56819f355a407f807b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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