フルオロメチルオキシラン

1,2-Epoxy-3-fluoropropane

HCID 10418CAS 503-09-3

基本情報

標準SMILES
FCC1CO1
InChIKey
OIFAHDAXIUURLN-UHFFFAOYSA-N
分子式
C3H5FO
平均分子量
76.07 g/mol
単同位体質量
76.032443

概要

Epifluorohydrin is a clear colorless liquid. (NTP, 1992)

名称と識別子

優先名称
1,2-Epoxy-3-fluoropropane
IUPAC
2-(fluoromethyl)oxirane
現地名
フルオロメチルオキシラン
英語名
Epifluorohydrin
分子式
C3H5FO
分子量
76.07

名称と別名

Epifluorohydrin1,2-EPOXY-3-FLUOROPROPANEOxirane, (fluoromethyl)-3-Fluoropropene-1,2-oxidePropane, 1,2-epoxy-3-fluoro-CCRIS 60340ZZ4ROH5ILBRN 0102460oxirane, 2-(fluoromethyl)-EINECS 207-960-1NSC 21303FLUOROMETHYLOXIRANE
名称をさらに表示
3-フルオロプロピレンオキシドエピフルオロヒドリン1,2-エポキシ-3-フルオロプロパン2-(フルオロメチル)オキシランフルオロメチルオキシラン2-フルオロメチルオキシランWLN: T3OTJ B1FEpifluorhydrineepifluorohydrinecycloxyfluoropaneFLUOROMETHYLOXIRANEpifluorohydrin98%Epifluorohydrin,97%EPIFLUOROHYDRIN 97%
3-FLUOROPROPYLENE OXIDENSC-21303NSC-886085-17-01-00019 (Beilstein Handbook Reference)J1.567IDTXSID4025244RefChem:4118281-fluoro-2,3-epoxypropane

データベース識別子

CAS
503-09-3
PubChem CID
10418
DTXSID
DTXSID4025244
UNII
0ZZ4ROH5IL
EC Number
207-960-1
Nikkaji
J1.567I

物性

構造計算による物性

XLogP
-0.2
極性表面積
12.5 Ų
水素結合供与体数
0
水素結合受容体数
2
回転可能結合数
1
重原子数
5

実験および物理化学的性質

SpringerMaterials PropertiesBoiling point
LogP-0.16
Density1.09 at 68 °F (NTP, 1992) - Denser than water; will sink
Solubilitygreater than or equal to 100 mg/mL at 61 °F (NTP, 1992)
Flash Point40 °F (NTP, 1992)
Boiling Point185 to 187 °F at 760 mmHg (NTP, 1992)

物理化学的性質

沸点
85 · 85-86 °C (lit.)
比重(密度)
1.067 g/mL · 1.067 g/mL at 25 °C (lit.)
屈折率
20 · n20/D 1.368(lit.)
闪点
40 °F · 40 °F
貯蔵温度
0 · 0-6°C
外見
liquid

化学的性質

化学的特性clear colourless liquid

安全と法規制

GHS分類

GHS Classification · 4 件

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P270, P271, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P330, P361+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 44 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

DOT LabelFlammable Liquid Poison
Fire HazardsThis chemical is flammable. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: This compound is a lacrimator. When heated to decomposition it emits toxic fumes. (NTP, 1992)
Reactive GroupHalogenated Organic Compounds
Reactivity AlertsHighly Flammable
Reactivity Profile · 1 件

A halogenated epoxide. Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts. The chlorinated derivative has been shown to be incompatible with aniline, strong oxidizers, sulfuric acid, isopropylamine, zinc, aluminum, iron, etc. see epichlorohydrin.

安全と保護具

Fire FightingFires involving this material can be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Personal Protective Equipment (PPE) · 1 件

RECOMMENDED RESPIRATOR: When working with this chemical, wear a NIOSH-approved full face chemical cartridge respirator equipped with the appropriate organic vapor cartridges. If that is not available, a half face respirator similarly equipped plus airtight goggles can be substituted. However, please note that half face respirators provide a substantially lower level of protection than do full face respirators. (NTP, 1992)

安全データ

wgk
3
rtecs
TZ3325000
ridadr
UN 2924 3/PG 2
hs_code
2910900090
risk_code
11-23/24/25-34
hazard_code
F,T

化学と産業

応用分野

使用Epifluorohydrin is used as a reagent in the synthesis of N-arylphosphoramidates. In addition, it is used in the synthesis of orally bioavailable ALK inhibitors in the treatment of tumors.

一般的な説明Clear colorless liquid.

サプライヤー42 社

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常州新氟化学有限公司13275212658 · [email protected]
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関連反応

19 件

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