Magnesium Stearate → Naloxone Fentanyl

HRID 68194

反応式

HRID 68194 の反応式
[CH3:1][CH2:2][C:3]([N:5]([CH:12]1[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:14][CH2:13]1)[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1)=[O:4].[CH2:26]([C:30](O)([C:35]([OH:37])=O)[CH2:31][C:32]([OH:34])=O)[C:27]([OH:29])=O.[C:39]([O-])(=O)[CH2:40]CCCCCCCCCCCCCCCC.[Mg+2].C([O-])(=[O:78])CCCCCCCCCCCCCCCCC>>[CH2:12]=[CH:17][CH2:16][N:15]1[C@@H:18]2[CH2:19][C:20]3[CH:21]=[CH:22][C:23]([OH:78])=[C:32]4[O:34][C@H:26]5[C:27]([CH2:39][CH2:40][C@:35]2([OH:37])[C@:30]5([C:31]=34)[CH2:13][CH2:14]1)=[O:29].[CH3:1][CH2:2][C:3]([N:5]([CH:12]1[CH2:13][CH2:14][N:15]([CH2:18][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH2:16][CH2:17]1)[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1)=[O:4]

参加物

3

反応物 2

HCID 11177Magnesium StearateHCID 13810Fentanyl Citrate

生成物 1

HCID 86641843Naloxone Fentanyl

実験手順

Fentanyl citrate was added to the carrier material in amounts corresponding to a batch size of 300 tablets. Mixing was carried out under the same conditions as those described in Example 1. Croscarmellose sodium and silicified microcrystalline cellulose, and then magnesium stearate, were added and admixed under the same conditions as those described in Example 1.

後処理

  1. additionMixing

出典と根拠

ORDレコード
ord-4dd9c14257d746a4973130c2e6fabeb5
出典データセット
uspto-grants-2014_09
特許番号
US08821914B2

関連ノート

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