8-メチルキノリン

8-Methylquinoline

HCID 11910CAS 611-32-5

基本情報

標準SMILES
Cc1cccc2cccnc12
InChIKey
JRLTTZUODKEYDH-UHFFFAOYSA-N
分子式
C10H9N
平均分子量
143.18 g/mol
単同位体質量
143.07349929

概要

8-methylquinoline appears as yellow liquid or oil. (NTP, 1992)

名称と識別子

優先名称
8-Methylquinoline
IUPAC
8-methylquinoline
現地名
8-メチルキノリン
英語名
8-Methylquinoline
分子式
C10H9N
分子量
143.19

名称と別名

8-METHYLQUINOLINE611-32-5Quinoline, 8-methyl-DTXSID8020888CHEBI:48984NSC-9409K97B12J636DTXCID80888RefChem:107278210-264-0O-Toluquinoline8-methyl-quinoline
名称をさらに表示
8-メチルキノリンo-トルキノリン8‐メチルキノリン8-メチルキノリン (O-TOLUQUO-トルキノリンOOCTANE (1000ΜG/ML)8-methyquinoline8-Methyl0-Toluquinoline8-Methylchinolin8-methyl-quinolin8-Methylquinoline>8-Methylquinoline,98+%
CCRIS 408MFCD000068101199266-77-7NSC 9409CHEMBL1702610Quinoline, 8-methyl-, labeled with deuteriumNSC9409EINECS 210-264-0

データベース識別子

CAS
611-32-5
PubChem CID
11910
DTXSID
DTXSID8020888
ChEMBL
CHEMBL1702610
ChEBI
CHEBI:48984
UNII
K97B12J636
EC Number
210-264-0
Nikkaji
J841I

物性

構造計算による物性

XLogP
2.6
極性表面積
12.9 Ų
水素結合供与体数
0
水素結合受容体数
1
回転可能結合数
0
重原子数
11

実験および物理化学的性質

SpringerMaterials PropertiesBoiling point
LogP2.6
Density1.0719 at 68 °F (NTP, 1992) - Denser than water; will sink
Solubility1 to 5 mg/mL at 63 °F (NTP, 1992)
Flash Point221 °F (NTP, 1992)
Boiling Point478 °F at 751 mmHg (NTP, 1992)

物理化学的性質

融点
-80 °C · -80 °C
沸点
245 °C · 245 °C
比重(密度)
1.052 g/mL · 1.052 g/mL at 25 °C(lit.)
屈折率
20 · n20/D 1.614(lit.)
闪点
221 °F · 221 °F
貯蔵温度
Room Temperature

化学的性質

化学的特性clear yellow liquid

安全と法規制

GHS分類

GHS Classification · 4 件

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 2 件

Chemical: Quinoline, 8-methyl-

Quinoline, 8-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Quinoline, 8-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Fire HazardsThis chemical is combustible. (NTP, 1992)
Health HazardsSYMPTOMS: This compound may be absorbed through the skin and it causes skin irritation. The vapor or mist is irritating to the eyes, mucous membranes and upper respiratory tract.
Reactive GroupAmines, Phosphines, and Pyridines
Reactivity Profile · 1 件

8-METHYLQUINOLINE may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids (NTP, 1992). Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Air and Water ReactionsSlightly soluble in water.

安全と保護具

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 件

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

安全データ

wgk
3
tsca
TSCA listed
rtecs
VC0562000
hs_code
29334900
risk_code
36/37/38-68-22
化審法
(5)-796

化学と産業

用途と製造

U.S. Production2023: 10,582 lb
Industry UsesCorrosion inhibitor
General Manufacturing Information · 2 件

All Other Chemical Product and Preparation Manufacturing

Quinoline, 8-methyl-: ACTIVE

応用分野

使用8-Methylquinoline has been used in preparation of osmium chloridophosphine complexes, as quinoline carbene tautomers.Tumorigenic potential of 8-methylquinoline has been evaluated in newborn CD-1 mice and Sprague-Dawley rats.

一般的な説明Yellow liquid or oil.

調製方法

純化方法Purify it as for 2-methylquinoline. The phosphate and picrate have m 158o and m 201o, respectively. [Beilstein 20 III/IV 3500, 20/7 V 405.]

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海策嵘生物科技有限公司[email protected]
Changzhou Carman Chemical Co., Ltd.15061933924

補足説明

定義ChEBI: A methylquinoline carrying a methyl substituent at position 8.

関連反応

25 件

関連ノート

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