三硝酸アルミニウム

greater than 1 at 68 °F (USCG, 1999)

1.72 @25 °C

On decomposition it emits toxic /nitrogen oxides/.

Decomposes in hot water.

163 °F (USCG, 1999)

Melting point 73.5 °C. Decomposition to nitric acid and basic aluminum nitrates ... begins at 130 °C. Dissociation to aluminum oxide and oxides of nitrogen occurs above 500 °C. /Nonahydrate/

73 °C

Odor Threshold Low: 0.01 [mg/m3]

Odor perception threshold for aluminum nitrate appeared to be the concentration of 0.1 mg/L.

Aluminum nitrate appears as a white, crystalline solid. Noncombustible but can accelerate the burning of combustible materials. If large quantities are involved or the combustible material is finely divided, an explosion may result. Prolonged exposure to fire or heat may result in an explosion. Fires that involve this material, produce oxides of nitrogen. Uses include, petroleum refining, dyeing, and leather tanning.

Liquid

White crystals; [CAMEO]

Nonahydrate /state/ is the most stable. /Nonahydrate/

Low melting solids or colorless, volatile liquids. /Alkylaluminum halides/

Less sensitive than trialkylaminums to oxidation upon exposure to air. /Alkylaluminum halides/

Deliquescent crystals; mp 73 °C; decomposes @ 135 °C. Very soluble in water, alcohol; very slightly soluble in acetone. Almost insoluble in ethyl acetate and pyridine. The aqueous solution is acid. /Nonahydrate/

White crystals; decomposes at 150 °C. Decomposes in hot water. /Nonahydrate/

This chemical does not meet GHS hazard criteria for 6.3% (24 of 378) of reports.

Danger

H301 (24.3%): Toxic if swallowed [Danger Acute toxicity, oral]

P203, P264, P264+P265, P270, P280, P301+P316, P302+P352, P305+P351+P338, P305+P354+P338, P317, P318, P321, P330, P332+P317, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 378 reports by companies from 16 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Chemical: Nitric acid, aluminium salt

Commission Regulation (EC) No 2229/2004

Nitric acid, aluminum salt (3:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Nitric acid, aluminum salt (3:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 05-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/13747

Nitric acid, aluminium salt: HSNO Approval: HSR001308 Approved with controls

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fire.

CAUTION: Ammonium nitrate products may explode if involved in fire or contaminated with hydrocarbons (fuels), organic matter, other contaminants or when hot molten and contained. Treat as an explosive (GUIDE 112).

FIRE HAZARD: Moderate, by spontaneous chemical reaction; practically all nitrates are powerful oxidizing agents ... . /Nitrates/

Certain polymerization catalysts, such as aluminum alkyls, react & burn violently on contact with water. /Aluminum alkyls/

Aluminum alkyls are organic aluminum compounds that are highly reactive and dangerous because of spontaneous burning in air. /Aluminum alkyls/

Prophoric material in flammable solvent. Vapors are heavier than air & may travel to a source of ignition & flash back. /Aluminum alkyls/

Ingestion of large doses causes gastric irritation, nausea, vomiting, and purging. Contact with dust irritates eyes and skin. (USCG, 1999)

· Inhalation, ingestion or contact (skin, eyes) with vapors or substance may cause severe injury, burns or death.

A skin and eye irritant; Causes vomiting and purging after ingestion; [CAMEO] Causes reproductive effects and weight loss in feeding studies in experimental animals; [HSDB] Not combustible, but as a strong oxidizer it may cause other materials to ignite. A respiratory tract irritant; Infants are more sensitive to nitrate ion toxicity; [MSDSonline] See NITRATES and NITRITES. See Aluminum.

Anon; Information profiles on Potential Occupaional Hazards: Aluminum & Compounds, 2nd Draft (Revised); GRA & I Issue 21 NTIS/PB89-216238 (1989)> TD3: Information profiles are working papers used by the National Institute for Occupational Safety and Health to assist the Institute in establishing priorities. The proile summarizes data on organic and inorganic substances containing aluminum as the only metal. Each summary presents data on known and suspected health effects, the extent of worker exposure, physical and chemical properties and the industrial importance of the following aluminum compounds: aluminum metal, aluminum ammonium sulfate, aluminum chlorhydrate, aluminum chloride anhydrous, aluminum chloride hydrous, aluminum distearate, aluminum ethoxide, aluminum fluoride, aluminum hydride, aluminum hydroxide, aluminum nitrate, aluminum oxide, aluminum ortho-phosphate, aluminum potassium sulfate, aluminum silicate, aluminum sodium sulfate, aluminum sulfate, calcium aluminum silicate, diethylaluminum chloride, sodium aluminate, tri-n-butylaluminum, triethylaluminum, tri-n-hexylaluminum, triisobutylaluminum, tri-n-octylaluminum. Detailed literature searches are conducted to identify information to be used in the profile sumaries. Sponsored by National Inst. for Occupational Safety and Health, Rockville, MD.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep combustibles (wood, paper, oil, etc.) away from spilled material.

EYES: flush with water for at least 15 min.

General First Aid:

Evacuation: If fire becomes uncontrollable -- consider evacuation of one-half (1/2) mile radius.

If material on fire or involved in fire: Flood with water. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.

Stop flow of liquid before extinguishing fire. Use dry chemical or carbon dioxide. DO NOT use water as straight stream directly on spilled material. Water fog can be used to control fire. DO NOT use halogenated extinguishing agents on spilled material. Violent reaction may result. Use water spray to keep fire-exposed containers cool. Fight fire from protected location or maximum possible distance. /Aluminum Alkyls/

Do not store near combustible materials.

Keep well closed. /Nonahydrate/

In general, materials ... toxic as stored or which can decompose into toxic components ... Should be stored in cool ... ventilated place, out of ... sun, away from ... fire hazard ... be periodically inspected and monitored. Incompatible materials should be isolated ... .

Extremely reactive with air, moisture and compounds containing active hydrogen and therefore must be kept under a blanket of inert gas. /Aluminum alkyls/

For more Storage Conditions (Complete) data for ALUMINUM NITRATE (8 total), please visit the HSDB record page.

Aluminum compounds are treated under anhydrous conditions to prevent violent reactions, recover solvent, and form Al compounds suitable for landfill by reaction with anhydrous hydrolysis agent, eg calcium hydroxide. /Aluminum compounds/

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Personnel protection: ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. Wear positive pressure self-contained breathing apparatus when fighting fires involving this material.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Work clothing that becomes wet or significantly contaminated should be removed and replaced. /Aluminum (soluble salts and alkyls, as Al)/

For more Preventive Measures (Complete) data for ALUMINUM NITRATE (7 total), please visit the HSDB record page.

Excerpt from ERG Guide 140 [Oxidizers]:

Immediate precautionary measure

8 hr Time Weighted Avg (TWA): 1 mg/cu m, respirable fraction. /Aluminum metal and insoluable compounds/

A4: Not classifiable as a human carcinogen. /Aluminum metal and insouble compound/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Aluminum metal and insouble compounds/

Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution administered intravenously slowly over five minutes followed by IV flush with normal saline. Methylene blue restores the iron in hemoglobin to its normal (reduced) oxygen-carrying state. (L1613)

Aluminum targets the nervous system and causes decreased nervous system performance and is associated with altered function of the blood-brain barrier. The accumulation of aluminum in the body may cause bone or brain diseases. High levels of aluminum have been linked to Alzheimer's disease. A small percentage of people are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminium. Nitrate and nitrite poisoning causes methemoglobinemia. Nitrites may cause pregnancy complications and developmental effects. They may also be carcinogenic. (L1137, L739, L740)

LC50 Caenorhabditis elegans (Nematode) 79 mg/L/24 hr (95% confidence interval: 71-89 mg/L); static /technical product/

LC50 Caenorhabditis elegans (Nematode) 2 mg/L/48 hr (95% confidence interval: 1.9-2.6 mg/L); static /technical product/

LC50 Caenorhabditis elegans (Nematode) 1.9 mg/L/72 hr (95% confidence interval: 1.8-2.0 mg/L); static /technical product/

LC50 Caenorhabditis elegans (Nematode) 1.8 mg/L/96 hr (95% confidence interval: 1.6-1.9 mg/L); static /technical product/

Albic and spodic soil horizons were sampled from old growth eastern white pine/mixed northern hardwoods sites in the Adirondacks, and an ochric soil horizon was sampled from the Appalachian Plateau of NY State. 9 Three-horizon forest floor, 9 mineral soil (field moist equivalent of 12.0 oven-dry albic, spodic, or ochric mineral soil) and 9 forest floor/mineral soil columns were leached with 60 ml of (a) 10 mM ammonium nitrate (control), (b) 1.0 mM nitric acid in 10 mM ammonium nitrate (pH 3), and (c) 1.0 mM ammonium nitrate (pH 3) at the rate of 10 ml/h. The above procedure was repeated on each mineral soil without a forest floor, except leaching soln were 0.5 mM calcium nitrate or calcium sulfate, each in 10 mM ammonium nitrate. Adding 2 and 0.5 cmol sub c (H+)/kg to forest floor and mineral soils, respectively, simulated snowmelt additions. Total aluminum concn in leachates from forest floor/albic or forest floor/ochric columns were greater than the sum of concn in leachates from the forest floor and mineral horizon when leached separately. This positive synergistic behavior of the forest floor-mineral horizon sequences was also observed in the forest floor-spodic horizon sequence when leached with control soln, but the synergism was negative for both labile and non-labile aluminum when leached with the acids. Sulfuric acid leached less aluminum from the spodic horizon than did nitric acid, regardless of the presence of a forest floor, but nitric acid, sulfuric acid , and control soln leached similar concn of aluminum from the albic and ochric horizons. The forest floor effects on the mineral soil leachates were attributed to effects of calcium, sulfate, nitrate, and dissolved organic C leached from the forest floor to the mineral horizon since forest floor removed nearly all added H+. /Aluminum/

The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphorus. The decreased phosphate body burden results in osteomalacia (softening of the bones due to defective bone mineralization) and rickets. Aluminum's neurotoxicity is believed to involve several mechanisms. Changes in cytoskeletal protein functions as a results of altered phosphorylation, proteolysis, transport, and synthesis are believed to be one cause. Aluminum may induce neurobehavioral effects by affecting permeability of the blood-brain barrier, cholinergic activity, signal transduction pathways, lipid peroxidation, and impair neuronal glutamate nitric oxide-cyclic GMP pathway, as well as interfere with metabolism of essential trace elements because of similar coordination chemistries and consequent competitive interactions. Aluminum can also interact with estrogen receptors, increasing the expression of estrogen-related genes and contributing to the progression of breast cancer. Certain aluminum salts induce immune responses by activating inflammasomes. Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as methemoglobinemia, and is characterized by tissue hypoxia, as methemoglobin cannot bind oxygen. (A2450, L1613, L739, A235, A236)

Two levels of phosphorus (20 and 80 kg P/ha) and 2 levels of aluminum (0 and 85 kg Al/ha, as aluminum nitrate) were applied to Enders soils of pH 4.4, 6.6, or 7.3. 16-day-old vegetable amaranth (Amaranthus iricolor L.) plants were transplanted 24 July 1986 and harvested 27 days later. Adding Al to the soil decr plant height (p = 0.05), leaf blade chlorophyll (p = 0.05), Nitrogen (p = 0.05), phosphorus (p = 0.01), and sodium (p = 0.05), but increased manganese (p = 0.05). At the termination of the expt, exchangeable soil Al was found only in soil at pH 4.4 (1.1 cmol/kg). The highest leaf blade Al concn (2473 mg/kg) was found in soil at pH 6.6 that received the low rate of supplemental P. Regardless of soil pH, leaf blade Al was negatively correlated with plant height (r = -0.78), plant dry wt (r = 0.78), available soil P (r = -0.51), and leaf blade P (r = -0.53), but it was positively correlated with Fe (r = 0.98).

Inhalating aluminum dust causes coughing and abnormal chest X-rays. A small percentage of people are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminium. Nitrate and nitrite poisoning causes methemoglobinemia. Symptoms include cyanosis, cardiac dysrhythmias and circulatory failure, and progressive central nervous system (CNS) effects. CNS effects can range from mild dizziness and lethargy to coma and convulsions. (L1137, L739, L740)

/SIGNS AND SYMPTOMS/ Ingestion of large doses causes gastric irritation, nausea, vomiting, and purging.

/SIGNS AND SYMPTOMS/ Contact with dust irritates eyes and skin.

(AZ) ARIZONA 73 ug/l /Aluminum/

(CA) CALIFORNIA 200 ug/l /Aluminum/

(ME) MAINE 1430 ug/l /Aluminum/

Aluminum is poorly absorbed following either oral or inhalation exposure and is essentially not absorbed dermally. The bioavailability of aluminum is strongly influenced by the aluminum compound and the presence of dietary constituents which can complex with aluminum and enhance or inhibit its absorption. Aluminum binds to various ligands in the blood and distributes to every organ, with highest concentrations found in bone and lung tissues. In living organisms, aluminum is believed to exist in four different forms: as free ions, as low-molecular-weight complexes, as physically bound macromolecular complexes, and as covalently bound macromolecular complexes. Absorbed aluminum is excreted principally in the urine and, to a lesser extent, in the bile, while unabsorbed aluminum is excreted in the faeces. Intake of some amount of nitrates and nitrites is a normal part of the nitrogen cycle in humans. In vivo conversion of nitrates to nitrites can occur in the gastrointestional tract under the right conditions, significantly enhancing nitrates' toxic potency. The major metabolic pathway for nitrate is conversion to nitrite, and then to ammonia. Nitrites, nitrates, and their metabolites are excreted in the urine. (L1137, L739)

...No significant diferences were found in alumium uptake and distribution and its effect on lactate dehydragenase leakage and lactate formation when the metal ion was given as aluminum chloride, aluminum nitrate, or Al (lactate)3. Aluminum concentrations (AlCl2) >250 uM severely disturbed the determination of lactate dehdrogenase AST and lactate in a cell-free system. ...

Young (21 days old), adult (8 months), and old (16 months) rats were exposed to 50 and 100 mg aluminum/kg bw administered as aluminum nitrate in drinking water for a period of 6 months. Brain concentrations were found to be higher in young rats. Urinary aluminum levels of old rats tended to increase.

Following a single maximum safe oral dose of the water soluble compounds aluminum chloride (333 mg Al/kg), aluminum nitrate (934 mg Al/kg), aluminum citrate (1,081 mg Al/kg), and aluminum lactate (2,942 mg Al/kg) in rabbits, aluminum absorption was 0.57, 1.16, 2.18, and 0.63%, respectively.

Aluminium nitrate was administered in the drinking water of four groups of 10 female SD rats for one month at the following doses: 0, 375, 750, or 1500 mg/kg bw/day. Food and water consumption and urine volume were measured daily. Body weight and protein efficiency coefficients were calculated each week. On days 10, 20, and 30, blood was analyzed. At necropsy various tissues were sampled, examined histopathologically, weighed and aluminium content determined by atomic absorption spectrophotometry. Rats fed 1500 mg aluminium/kg bw/day excreted less urine (6 +/- 2 mL) than control rats (35 +/- 14 mL). There were no significant differences in relative organ weights between treated and control rats. Blood parameters were unchanged by aluminium treatment. Although tissue aluminium concentration was generally higher in treated animals the increases were only significant for spleen, heart, stomach and small and large intestine in rats receiving the highest aluminium concentration.

For more Absorption, Distribution and Excretion (Complete) data for ALUMINUM NITRATE (7 total), please visit the HSDB record page.

Used in petroleum refining, dyeing, and leather tanning; [CAMEO] Used in antiperspirants and corrosion inhibitors; also used as a nitrating agent and in uranium extraction; [Merck Index]

Petroleum Production and Refining [Category: Industry]

Tanning leather; antiperspirant; corrosion inhibitor; extraction of uranium; nitrating agent.

Textiles (mordant), manufacture of incandescent filaments; catalyst in petroleum refining; nucleonics. /Nonahydrate/

Salting-out agent in the extraction of actinides. /Nonahydrate/

Source of alumina used in the preparation of insulating papers, on transformer core laminates, and in cathode ray tube heating elements. /Nonahydrate/

Formed by action of nitric acid on aluminum and crystallization. /Nonahydrate/

... Prepared by dissolving aluminum or aluminum hydroxide in dilute nitric acid, and crystallizing the product from the resulting aqueous solution. /Nonahydrate/

Made commercially from aluminous materials such as bauxite. /Nonahydrate/

Fabricated Metal Product Manufacturing

Nitric acid, aluminum salt (3:1): ACTIVE

Occurs in several states of hydration of which nonhydrate is most stable.