CAS 10025-73-7 Chromium(3+) trichloride (HCID 6452300)

基本情報

CAS: 10025-73-7
標準SMILES: [Cl-].[Cl-].[Cl-].[Cr+3]
InChIKey: QSWDMMVNRMROPK-UHFFFAOYSA-K
分子式: Cl3Cr
平均分子量: 158.35 g/mol

概要

Chromium(3+) trichloride is a chromium chloride with the chromium cation in the +3 oxidation state. It has a role as a sensitiser and a Lewis acid.

名称と識別子

優先名称: Chromium(3+) trichloride
IUPAC: chromium(3+) trichloride
英語名: chromium chloride
分子式: ClCr-
分子量: 158.36

名称と別名

chromium(3+) trichloride39345-92-1Cl3CrChromium(iii)chloridetris(chloranyl)chromiumChromium(III); chlorideSCHEMBL49822CHROMIC CHLORIDE [MI]CHEBI:53351CHROMIC CHLORIDE [WHO-DD]AKOS024437430DB09129

名称をさらに表示

CHROMIUM CHLORIDE

CHROMIC CHLORIDE ANHYDROUS [HSDB]Chromium(III) chloride pound CrCl3 pound(c)F099239F987909

データベース識別子

CAS: 10025-73-7、39345-92-1、50925-66-1
PubChem CID: 6452300
ChEBI: CHEBI:53351
UNII: Z310X5O5RP
Nikkaji: J43.774C

物性

構造計算による物性

極性表面積: 0 Å²
水素結合供与体数: 0
水素結合受容体数: 3
回転可能結合数: 0
重原子数: 4
形式電荷: 0
複雑度: 0

化学と産業

薬理情報

Protein BindingChromic chloride-induced binding of protein to red cells.

Pharmacodynamics · 1 件

Trivalent chromium is part of glucose tolerance factor, an essential activator of insulin-mediated reactions. Chromium helps to maintain normal glucose metabolism and peripheral nerve function. Providing chromium during TPN helps prevent deficiency symptoms including impaired glucose tolerance, ataxia, peripheral neuropathy and a confusional state similar to mild/moderate hepatic encephalopathy.

Mechanism of Action · 1 件

Metallic chromium has no biological activity. Chromium is referred as a glucose tolerance factor. This glucose tolerance factor is a complex of molecules. Glycine, cysteine, glutamic acid and nicotinic acid along with chromium form this complex.

Biological Half-Life31- 41 hours

Metabolism/Metabolites · 1 件

The metabolism of chromic chloride hexahydrate in guinea pigs for 60 days after intratracheal injection of 200 ug Cr 10 min after injection, 69% of the dose remained in the lungs, & only 4% was found in the blood & liver, kidneys, spleen. By 24 hr, 45% was still in the lungs, 6% was excreted in the urine, & only a very small % was found in the other tissues. The spleen was the only tissue that showed accumulation & that occurred during the 1st 48 hr.

Absorption, Distribution and Excretion · 3 件

Chromium absorption can increase with exercise.

Most absorbed chromium is excreted rapidly in the urine, whereas unabsorbed chromium is excreted through feces.

Chromium is stored in liver, spleen, soft tissue and bone.