Trimethylsilanol (HCID 66110)

概要

RN given refers to parent cpd

名称と識別子

優先名称: Trimethylsilanol
IUPAC: hydroxy(trimethyl)silane
現地名: トリメチルシラノール
英語名: hydroxytrimethylsilane
分子式: C3H10OSi
分子量: 90.2

名称と別名

Trimethylsilanol1066-40-6HydroxytrimethylsilaneSilanol, trimethyl-TrimethylhydroxysilaneSilanol, 1,1,1-trimethyl-Z4BIN3300PDTXSID7061433RefChem:191810DTXCID3033010213-914-1hydroxy(trimethyl)silane

名称をさらに表示

トリメチルシラノールトリメチルヒドロキシシラントリメチルシラノルトリメチルシラノ?ルTMSOHDK031LS 310SilanoleTrimethylsilanol,95%

C3H10OSiMFCD02751657CCRIS 1320EINECS 213-914-1UNII-Z4BIN3300PTrimethylsilanotrimethyl silanoltrimethyl-silanol

データベース識別子

CAS: 1066-40-6
PubChem CID: 66110
DTXSID: DTXSID7061433
ChEMBL: CHEMBL4238997
UNII: Z4BIN3300P
EC Number: 213-914-1
Nikkaji: J555J

物性

構造計算による物性

極性表面積: 20.2 Å²
水素結合供与体数: 1
水素結合受容体数: 1
回転可能結合数: 0
重原子数: 5
形式電荷: 0
複雑度: 28.4

実験および物理化学的性質

Chemical ClassesMetals -> Metalloid Compounds (Silicon)

SpringerMaterials Properties29Si nuclear magnetic resonance spectrum

Vapor Pressure0.14 [mmHg]

Food Contact SubstancesFCS -> FDA Cumulative Estimated Daily Intake (CEDI)

Physical DescriptionColorless liquid with a strong odor; [Wacker Silicones MSDS]

物理化学的性質

融点: -4.5 °C · -4.5 °C
沸点: 90 ℃/760Torr · 90℃/760Torr
比重(密度): 0.95 · 0.950
蒸気圧: 19 · 19-55hPa at 25℃
屈折率: 1.3889 · 1.3889
闪点: 4 ° · 4°(39°F)
貯蔵温度: -20 °C · Sealed in dry,Store in freezer, under -20°C
溶解性: Chloroform (Sparingly), DMSO (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
外見: liquid
酸解離定数(Pka): 12.67 · 12.67±0.58(Predicted)
比重: 0.8139 · 0.8139
色: Clear, colourless
水溶解度: 水に溶けます (1.00 mg/ml)。
BRN: 1361356 · 1361356
Henry's Law Constant: 7 · 7.0×10-2 mol/(m3Pa) at 25℃, Xu and Kropscott (2014)
InChI: 1S/C3H10OSi/c1-5(2,3)4/h4H,1-3H3
InChIKey: AAPLIUHOKVUFCC-UHFFFAOYSA-N
SMILES: C[Si](C)(C)O
LogP: 1.19 · 1.19-5.06 at 20-25℃
NISTの化学物質情報: Silanol, trimethyl(1066-40-6)
EPAの化学物質情報: Silanol, trimethyl- (1066-40-6)

化学的性質

化学的特性Colorless clear liquid

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 2.2% (5 of 232) of reports.

Danger

H225 (97.8%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P304+P340, P317, P319, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 232 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Not Classified

危険有害性情報

Regulatory Information · 4 件

Chemical: Silanol, trimethyl-

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 02-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23873

Silanol, trimethyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards Summary · 1 件

Reduced spontaneous motor activity, staggering gait, and decreased body weight observed in 28-day oral study of rats at the highest tested dose (640 mg/kg/day); No evidence of mutagenicity; [JECDB] Contains 10-30% hexamethyl disiloxane (CAS# 107-46-0) as an impurity; May cause mild eye irritation; [Wacker Silicones MSDS] See Hexamethyldisiloxane and Dimethylsilane.

Hazard Classes and Categories · 2 件

Flam. Liq. 2 (97.8%)

Flammable liquids - Category 2

安全と保護具

Protective Action Criteria (PAC) · 3 件

2.1 [ppm]

23 [ppm]

140 [ppm]

毒性情報

Adverse EffectsNeurotoxin - Other CNS neurotoxin

安全データ

wgk: 1
tsca: TSCA listed
ridadr: UN 1993BF 3 / PGII
hs_code: 29319090
risk_code: 11
化審法: 2-589
hazard_code: F
hazard_class: 3
Hazard Classifications: Acute Tox. 4 InhalationAquatic Chronic 3Flam. Liq. 2
ストレージクラス: 3 - Flammable liquids

化学と産業

用途と製造

UsesUsed as a chemical intermediate; [Wacker Silicones MSDS]

General Manufacturing InformationSilanol, 1,1,1-trimethyl-: ACTIVE

応用分野 · 3 件

解説C3H10OSi(90.20)．(CH3)3SiOH．トリメチルシラノールは，フルオロトリメチルシランをアルカリ加水分解すると得られる．無色の液体．沸点90～100 ℃．d420"0.8112．nD20"1.388．酸で加水分解すると容易にヘキサメチルジシロキサンになる．森北出版「化学辞典（第2版）

説明Trimethylsilanol has strong acidity compared with the corresponding carbon alcohols, can react with tetrahydrolithium aluminum, Si-OH bond can be reduced Si-H bond, can be used as a blocking agent for straight-chain polysiloxanes with hydrophobicity, it is the most important intermediate in the preparation of organosilicon alcohol salts and all kinds of polysiloxanes products including silicone oils, silicone rubbers and silicone resins, etc, and it has a wide range of application prospects.

使用Trimethylsilanol used as a hydrophobic coat on silicate surfaces. Used as an as an antimicrobial agent.

上流・下流製品情報

上流原料

trimethyl-trityl-silane Phosphonic acid, 1H-imidazol-1-yl-, diphenyl ester Silane, (4-butylphenyl)trimethyl-Silane, trimethyl[(trimethylsilyl)methoxy]-Carbamic acid, [(2R)-2-fluoro-3-(hydroxyphosphinyl)propyl]-, 1,1-dimethylethyl ester, monoammonium salt Bis(trimethylsilyloxy)-phosphine 9-(トリメチルシリル)-9H-フルオレン tert-ブチル(トリメチルシリル)ペルオキシド 1,1,1-トリフェニル-2,2,2-トリメチルジシラントリメチル(ベンジルオキシ)シラン 1H-Inden-1-yltrimethylsilane トリメチルシリルメタノール

下流製品

ヘキサメチルジシロキサン

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]

衢州润东化工有限公司0570-8789886 18892685668 · [email protected]

湖北永阔科技有限公司027-59223108 15972152991 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

南通润丰石油化工有限公司66017690 19952660367 · [email protected]

トリメチルシラノール

基本情報

概要