Formicin (HCID 69365)

名称と識別子

優先名称: Formicin
IUPAC: N-(hydroxymethyl)acetamide
現地名: アセトアミドメタノール
英語名: N-(HYDROXYMETHYL)ACETAMIDE
分子式: C3H7NO2
分子量: 89.09

名称と別名

N-(Hydroxymethyl)acetamide625-51-4FormicinAcetamide, N-(hydroxymethyl)-formaldehyde acetamideMETHYLAL ACETAMIDEEINECS 210-897-2RCG03A51MOBRN 0506226FORMICIN [MI]DTXSID502115434-02-00-00405 (Beilstein Handbook Reference)

名称をさらに表示

アセトアミドメタノールN-(ヒドロキシメチル)アセトアミドN-ヒドロキシメチルアセトアミドN-アセチルメタノールアミンAcetamidomethanol >Hydroxymethylacetamiden-(hydroxymethyl)-acetamidHYDROXYMETHYLACETAMIDE(N-)AcetaMide,N-(hydroxyMethyl)-N-(Hydroxymethyl)acetamide,97%

RefChem:600325DTXCID80134034210-897-2InChI=1/C3H7NO2/c1-3(6)4-2-5/h5H,2H2,1H3,(H,4,6AcetamidomethanolN-HydroxymethylacetamideN-AcetylmethanolamineMFCD00014417

データベース識別子

CAS: 625-51-4
PubChem CID: 69365
DTXSID: DTXSID50211543
UNII: RCG03A51MO
EC Number: 210-897-2
Nikkaji: J505C

物性

構造計算による物性

XLogP: -1
極性表面積: 49.3 Å²
水素結合供与体数: 2
水素結合受容体数: 2
回転可能結合数: 1
重原子数: 6
形式電荷: 0
複雑度: 52

物理化学的性質

融点: 48 · 48-52 °C
沸点: 165.17 °C · 165.17°C (rough estimate)
比重(密度): 1.14 · 1.14
屈折率: 1.4368 · 1.4368 (estimate)
貯蔵温度: Inert atmosphere,Room Temperature
溶解性: クロロホルム（少量、超音波処理）、DMSO（少量）、メタノール（少量）
酸解離定数(Pka): 13.28 · 13.28±0.10(Predicted)
外見: 結晶性
色: 白からオフホワイトへ
水溶解度: 溶ける
Merck: 14 · 14,4242
BRN: 506226 · 506226
InChIKey: HWJHZLJIIWOTGZ-UHFFFAOYSA-N
CAS データベース: 625 · 625-51-4(CAS DataBase Reference)

化学的性質

化学的特性white to light yellow crystalline powder

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.

Warning

H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 1 of 2 reports by companies.；There is 1 notification provided by 1 of 2 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Hazard Classes and CategoriesSkin Irrit. 2 (50%)；Eye Irrit. 2A (50%)；STOT SE 3 (50%)

安全データ

F: 10
wgk: 3
rtecs: AC3610000
hs_code: 2928009090
risk_code: 36/37/38
hazard_code: Xi
safety_code: 22-24/25-36-26
hazard_class: IRRITANT

化学と産業

応用分野

使用N-(Hydroxymethyl)acetamide (cas# 625-51-4) is used as a catalyst in the method for manufacturing sol-gel silica particles method for manufacturing coating substrate coated with silica particles.

調製方法 · 1 件

純化方法Recrystallise it from freshly distilled Me2CO, wash the crystals with dry Et2O and dry them in a vacuum desiccator over P2O5. RF 0.4 on paper chromatography with CHCl3/EtOH (2:8) as solvent and developed with ammoniacal AgNO3. It also crystallises in needles from EtOAc containing a few drops of Me2CO. It is hygroscopic and should be stored under dry conditions. [Bachmann et al. J Am Chem Soc 73 2775 1951, Walter et al. Chem Ber 99 3204 1966, Einhorn & Ladisch Justus Liebigs Ann Chem 343 265 1905, Beilstein 2 IV 405.]