ポリ(L-乳酸)
Lactide
基本情報
- CAS
33135-50-1- 標準SMILES
CC1OC(=O)C(C)OC1=O- InChIKey
JJTUDXZGHPGLLC-UHFFFAOYSA-N- 分子式
- C6H8O4
- 平均分子量
- 144.12 g/mol
- 単同位体質量
- 144.04225873
概要
Lactide is a member of dioxanes.
名称と識別子
- 優先名称
- Lactide
- IUPAC
- 3,6-dimethyl-1,4-dioxane-2,5-dione
- 現地名
- ポリ(L-乳酸)
- 英語名
- poly(L-lactide)
- 分子式
- C6H8O4
- 分子量
- 144.12532
名称と別名
95-96-5LACTIDEDilactidep-Dioxane-2,5-dione, 3,6-dimethyl-RefChem:57699202-468-33,6-Dimethyl-1,4-dioxane-2,5-dioneDL-LactideDL-Dilactide33135-50-11,4-Dioxane-2,5-dione, 3,6-dimethyl-3,6-Dimethyl-2,5-dioxo-1,4-dioxane
名称をさらに表示
ポリ(L-乳酸), MW 700,000ポリ(L-乳酸), MW 325,000〜460,000ポリ-(L-ラクチド)ポリ(L-乳酸)L-polylactidePoly(L-lactide) PLLARESOMER?L 210poly-l-lactidLACTEL BP-0600PURASORB(R) PLPURASORB(R) PL8PURASORB(R) PL6PURASORB(R) PL4PURASORB(R) PL2
Lactic acid, bimol. cyclic esterLACTIDE, DL-Propanoic acid, 2-hydroxy-, bimol. cyclic ester7EH08MWO6MMFCD00011685DTXSID7041253AI3-05059NSC-403080
データベース識別子
- CAS
33135-50-1、95-96-5- PubChem CID
- 7272
- DTXSID
DTXSID7041253- ChEMBL
CHEMBL3185272- ChEBI
CHEBI:177651- UNII
- 7EH08MWO6M
- EC Number
- 202-468-3、608-832-1
- Nikkaji
- J4.715E
物性
構造計算による物性
- XLogP
- 0.6
- 極性表面積
- 52.6 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 4
- 回転可能結合数
- 0
- 重原子数
- 10
- 形式電荷
- 0
- 複雑度
- 155
実験および物理化学的性質
Chemical ClassesOther Classes -> Other Organic Compounds
Physical Description
CBI
Solid; [Sigma-Aldrich MSDS]
物理化学的性質
- 融点
- 153 °C · 153 °C
- 比重(密度)
- 1.27 g/cm3 · 1.27 g/cm3
- 貯蔵温度
- 2 · 2-8°C
- 外見
- solid
- InChI
- InChI=1/C6H8O4/c1-3-5(7)10-4(2)6(8)9-3/h3-4H,1-2H3/t3-,4-/s3
- InChIKey
- BHIWKHZACMWKOJ-UHFFFAOYSA-N
- SMILES
- O1[C@@H](C)C(=O)O[C@@H](C)C1=O |&1:1,6,r|
化学的性質
化学的特性White powder
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Warning
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
Aggregated GHS information provided per 158 reports by companies from 6 notifications to the ECHA C&L Inventory.
危険有害性情報
Regulatory Information
1,4-Dioxane-2,5-dione, 3,6-dimethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,4-Dioxane-2,5-dione, 3,6-dimethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Dilactide (EC: 202-468-3)
Hazards SummaryCauses stomach ulceration and changes in renal tubules in 2-week intermittent oral studies of dogs; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS] See 4,4-Dimethyl-1,3-dioxane and 1,4-Dioxane.
Hazard Classes and CategoriesEye Irrit. 2A (100%)
安全データ
- wgk
- 3
- hs_code
- 29181990
- safety_code
- 22-24/25
- ストレージクラス
- 11 - Combustible Solids
化学と産業
用途と製造
UsesUsed to make polylactic acid and cosmetics; [ExPub: ECHA REACH Registrations]
U.S. Production2023: 100,000,000 - <500,000,000 lb
Consumer UsesIntermediate
Industry UsesIntermediate
General Manufacturing Information
Plastics Product Manufacturing
1,4-Dioxane-2,5-dione, 3,6-dimethyl-: ACTIVE
応用分野
使用Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.
一般的な説明Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.
関連反応
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化合物ノート
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