DL-ラクチド

Lactide

HCID 7272CAS 33135-50-1
部分構造検索類似構造を探す

基本情報

標準SMILES
CC1OC(=O)C(C)OC1=O
InChIKey
JJTUDXZGHPGLLC-UHFFFAOYSA-N
分子式
C6H8O4
平均分子量
144.12 g/mol
単同位体質量
144.04225874

概要

Lactide is a member of dioxanes.

名称と識別子

優先名称
Lactide
IUPAC
3,6-dimethyl-1,4-dioxane-2,5-dione
現地名
DL-ラクチド
英語名
DL-Lactide
分子式
C6H8O4
分子量
144.13

名称と別名

95-96-5LACTIDEDilactidep-Dioxane-2,5-dione, 3,6-dimethyl-RefChem:57699202-468-33,6-Dimethyl-1,4-dioxane-2,5-dioneDL-Lactide33135-50-1DL-Dilactide1,4-Dioxane-2,5-dione, 3,6-dimethyl-3,6-Dimethyl-2,5-dioxo-1,4-dioxane
名称をさらに表示
DL-ラクチドrac-(2R*,5R*)-2,5-ジメチル-1,4-ジオキサン-3,6-ジオンDL-ジラクチドrac-(2R*)-2α*,5α*-ジメチル-1,4-ジオキサン-3,6-ジオン(±)-ラクチド3,6-ジメチル-1,4-ジオキシン-2,5(3H,6H)-ジオン(±)-ジラクチド3,6-ジメチル-1,4-ジオキサン-2,5-ジオン2,5-ジメチル-1,4-ジオキサン-3,6-ジオンrac-3β*,6β*-ジメチル-1,4-ジオキサン-2,5-ジオンrac-ラクチドラクチドジラクチドrac-(3R*,6R*)-3,6-ジメチル-1,4-ジオキサン-2,5-ジオンrac-2α*,5α*-ジメチル-1,4-ジオキサン-3,6-ジオンrac-(3R*)-3β*,6β*-ジメチル-1,4-ジオキサン-2,5-ジオンDLラクチドDL-ラクチド, 99%LACTIC ANHYDRIDE2-hydroxy-propanoicacibimol.cyclicesterD,L-Lactide S5-Dione,3purasorbl
Lactic acid, bimol. cyclic ester7EH08MWO6MMFCD00011685Propanoic acid, 2-hydroxy-, bimol. cyclic esterDTXSID7041253AI3-05059LACTIDE, DL-NSC-403080

データベース識別子

CAS
33135-50-1、95-96-5
PubChem CID
7272
DTXSID
DTXSID7041253
ChEMBL
CHEMBL3185272
ChEBI
CHEBI:177651
UNII
7EH08MWO6M
EC Number
202-468-3、608-832-1
Nikkaji
J4.715E

物性

構造計算による物性

XLogP
0.6
極性表面積
52.6 Ų
水素結合供与体数
0
水素結合受容体数
4
回転可能結合数
0
重原子数
10

実験および物理化学的性質

Chemical ClassesOther Classes -> Other Organic Compounds
Physical Description · 2 件

CBI

Solid; [Sigma-Aldrich MSDS]

物理化学的性質

融点
116 · 116-119 °C
沸点
142 °C8 · 142 °C8 mm Hg(lit.)
比重(密度)
1.186 · 1.186±0.06 g/cm3(Predicted)
蒸気圧
0.311 Pa · 0.311Pa at 25℃
闪点
180 °C · 180°C
貯蔵温度
2 · 2-8°C

化学的性質

化学的特性White crystalline powder

安全と法規制

GHS分類

GHS Classification · 4 件

Warning

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)

Aggregated GHS information provided per 158 reports by companies from 6 notifications to the ECHA C&L Inventory.

危険有害性情報

Regulatory Information · 2 件

1,4-Dioxane-2,5-dione, 3,6-dimethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,4-Dioxane-2,5-dione, 3,6-dimethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 13-06-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/15774

Hazards SummaryCauses stomach ulceration and changes in renal tubules in 2-week intermittent oral studies of dogs; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS] See 4,4-Dimethyl-1,3-dioxane and 1,4-Dioxane.
Hazard Classes and CategoriesEye Irrit. 2A (100%)

安全データ

wgk
2
tsca
TSCA listed
rtecs
JH1100000
hs_code
29322090
risk_code
36/37/38-36
化審法
(5)-5295

化学と産業

用途と製造

UsesUsed to make polylactic acid and cosmetics; [ExPub: ECHA REACH Registrations]
U.S. Production2023: 100,000,000 - <500,000,000 lb
Consumer UsesIntermediate
Industry UsesIntermediate
General Manufacturing Information · 2 件

Plastics Product Manufacturing

1,4-Dioxane-2,5-dione, 3,6-dimethyl-: ACTIVE

応用分野 · 2 件

使用DL-Lactide is used to produce 2-hydroxy-propionic acid 1-(1-phenyl-ethoxycarbonyl)-ethyl ester. It acts as an important raw material and an intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyes. It is involved in enzymatic alcoholysis to produce both alkyl (R)-lactates and alkyl (S,S)-lactyllactates.

一般的な説明3,6-Dimethyl-1,4-dioxane-2,5-dione (or rac-lactide), is the 50:50 racemic mixture of D- and L-Lactide. Rac-lactide is a lactone derived from lactic acid that has attracted great interest in academia and commercial applications, as it is derived from abundant renewable resources. Rac-lactide can be ready polymerized via ring-opening polymerization, using a variety of metal or organocatalysts, yielding poly(D,L-lactide). While the resulting polymer is generally amorphous, the use of stereospecific catalysts can lead to heterotactic PLA, which exhibits some degree of crystallinity.

上流・下流製品情報

サプライヤー50 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
苏州启航生物科技有限公司18151111370 · [email protected]

補足説明

定義本品は、次の化学式で表される有機化合物である。

関連反応

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