Lactide → Poliglecaprone

HRID 379496

反応式

HRID 379496 の反応式
[CH2:1]1[O:8][C:6](=[O:7])[CH2:5][O:4][C:2]1=[O:3].[C:9]1(=[O:16])[O:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1.CCCCC(C([O-])=O)CC.CCCCC(C([O-])=O)CC.[Sn+2].C(O)CCCCCCCCC.CC1OC(=O)C(C)OC1=O>>[C:9]1(=[O:16])[O:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1.[CH2:1]1[O:8][C:6](=[O:7])[CH2:5][O:4][C:2]1=[O:3]

参加物

6

反応物 5

HCID 7272LactideHCID 81741-DecanolHCID 93182-ethylhexanoic acid tin(II) saltHCID 10401epsilon-CAPROLACTONEHCID 65432Glycolide2 回

生成物 1

HCID 65431Poliglecaprone

反応条件

温度
170 °C

実験手順

Glycolide (0.13 moles) was mixed with ε-caprolactone (1.18) and a catalytic amount of stannous octoate (0.262 mole) and 1-decanol (3.275 mole). The system was heated to 170° C. and was stirred at this temperature for 30 minutes. The reaction was then cooled to 120° C. Glycolide (0.65 moles) and dl-lactide (0.52 moles) were added to the prepolymer. After melting the second charge, the system was heated to 170° C. and was stirred at this temperature for 6.5 hours. At the conclusion of the reaction, the unreacted monomer was removed by heating at 130° C. under reduced pressure for 1.5 hours. The resulting polymer was characterized by DSC (for Tm), solution viscosity (for molecular dimensions), IR and NMR (for chemical composition).

後処理

  1. temperatureThe reaction was then cooled to 120° C
  2. temperaturethe system was heated to 170° C.
  3. stirringwas stirred at this temperature for 6.5 hours
  4. customAt the conclusion of the reaction
  5. customthe unreacted monomer was removed
  6. temperatureby heating at 130° C. under reduced pressure for 1.5 hours

出典と根拠

ORDレコード
ord-1c558c26d9dd4b188c9a0b7c258b08d4
出典データセット
uspto-grants-2001_10
特許番号
US06299631B1

関連ノート

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