(2S)-2α,3α,4β,5α-テトラヒドロキシテトラヒドロ-2H-ピラン-6β-メタノール
Alpha-D-Glucose
基本情報
- CAS
492-62-6- 標準SMILES
OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O- InChIKey
WQZGKKKJIJFFOK-DVKNGEFBSA-N- 分子式
- C6H12O6
- 平均分子量
- 180.16 g/mol
- 単同位体質量
- 180.0633881
概要
Amylose is a glucan composed of unbranched chains of D-glucopyranose residues in alpha(14) glycosidic linkage. The number of repeated glucose subunits (n) is usually in the range of 300 to 3000, but can be many thousands. One of the two components of starch (the other, 70-80%, being amylopectin). Cf. linear maltodextrin, in which the chain length is typically between 3 and 17 glucose units. It has a role as a mouse metabolite, a plant metabolite and an Escherichia coli metabolite.
名称と識別子
- 優先名称
- Alpha-D-Glucose
- IUPAC
- (2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
- 現地名
- (2S)-2α,3α,4β,5α-テトラヒドロキシテトラヒドロ-2H-ピラン-6β-メタノール
- 英語名
- Dextrose
- 分子式
- C6H12O6
- 分子量
- 180.16
名称と別名
alpha-D-glucose492-62-6alpha-D-Glucopyranosealpha-Dextrose(2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol5J5I9EB41ECHEBI:17925GlyTouCan:G58161NSDTXSID30197710RefChem:936358DTXCID90120201G58161NS
名称をさらに表示
(2S)-2α,3α,4β,5α-テトラヒドロキシテトラヒドロ-2H-ピラン-6β-メタノールα-D-グルコースD-ブドウ糖α-グルコースα-D-グルコピラノースΑ-D(+)-グルコース(無水)Α‐D(+)‐グルコース(無水)D-(+)-グルコース ぶどう糖D-グルコース無水物グルコース 溶液(2S,3R,4S,5S,6R)-6-(ヒドロキシメチル)オキサン-2,3,4,5-テトラオール(2S,3R,4S,5S,6R)-6-(ヒドロキシメチル)テトラヒドロ-2H-ピラン-2,3,4,5-テトラオールα-D-GlucoseD-GLCGLUCOSE STANDARDGlucose solutionGLUCOSUM
207-757-8607-980-4alpha-glucoseGlucopyranose, alpha-D-a-D-Glucose(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraolalpha-d(+)-glucose(1->3)-alpha-D-glucan
物性
構造計算による物性
- XLogP
- -2.6
- 極性表面積
- 110 Ų
- 水素結合供与体数
- 5
- 水素結合受容体数
- 6
- 回転可能結合数
- 1
- 重原子数
- 12
- 形式電荷
- 0
- 複雑度
- 151
実験および物理化学的性質
Chemical ClassesBiological Agents -> Monosaccharides and Derivatives
DrugsPharmaceuticals -> Metabolite of Sorbitol
CosmeticsSkin conditioning
SpringerMaterials PropertiesCrystal structure
Solubility500 mg/mL at 20 °C
Melting Point146 °C
Physical Description
White crystalline powder; Odorless; [Acros Organics MSDS]
Solid
Collision Cross Section
146.2 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
146.6 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
146.5 Ų [M+Na]+
物理化学的性質
- 融点
- 153 · 153-156 °C(lit.)
- 沸点
- 232.96 °C · 232.96°C (rough estimate)
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 98% (48 of 49) of all reports.
Not Classified
Aggregated GHS information provided per 49 reports by companies from 3 notifications to the ECHA C&L Inventory.
危険有害性情報
Regulatory Information
Chemical: .alpha.-D-Glucopyranose
.alpha.-D-Glucopyranose: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - .alpha.-D-Glucopyranose: Human health tier I assessment
Hazards SummaryMay cause irritation; [Acros Organics MSDS] See Glucose.
Hazard Classes and CategoriesNot Classified
安全データ
- F
- 3
- wgk
- 3
- rtecs
- LZ6600000
- hs_code
- 17023000
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36/37/39
- ストレージクラス
- 11 - Combustible Solids
化学と産業
薬理情報
Tissue LocationsEpidermis
Cellular LocationsCytoplasm
Metabolite PathwaysFanconi-bickel syndrome
用途と製造
Use ClassificationCosmetics -> Skin conditioning
応用分野
使用α-D-Glucose is used:As a reducing agent in the preparation superparamagnetic ferrous oxide (Fe3O4) nanoparticles and silver nanocrystals.As an additive for the formation of isoporous polystyrene-block-poly(4-vinylpyridine) (PS-b-P4VP) diblock copolymer membranes.For glycosylation of cell-penetrating poly(disulfide)s (CPDs) with improved solubility to achieve multifunctional cellular uptake.As a precursor in the synthesis of metal/carbon nanohybrids under hydrothermal conditions.
調製方法
純化方法Recrystallise -D-glucose slowly from aqueous 80% EtOH, then dry it over P2O5 in vacuo. Alternatively, crystallise it from water at 55o, then dry it for 6hours in a vacuum oven between 60-70o/2mm. Its solubilities are: H2O (~50%), EtOH (1.7%). [Hendricks et al. J Am Chem Soc 56 99 1934, Beilstein 1 IV 4302.] [For equilibrium forms see Angyal Adv Carbohydr Chem 42 15 1984, Angyal & Pickles Aust J Chem 25 1711 1972.]
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