3-Hydroxychalcone → HCID 12648138、化合物
反応式
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:11])[CH:5]=[CH:6][CH:7]=1>[Pd].C1COCC1>[OH:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:11])[CH:5]=[CH:6][CH:7]=1参加物
4
実験手順
The title compound was prepared as described in General Method 3 from 3-(3-hydroxy-phenyl)-1-phenyl-prop-2-en-1-one (8.0 g, 35.7 mmol), 5% Pd on BaSO4 (0.4 g), and THF (100 mL) at a reaction time of 2 hours. The crude product was purified by silica gel chromatography, eluting with EtOAc:hexane (10:90 to 25:75) to give the title compound, m.p. 81-83° C.
後処理
- customThe title compound was prepared
- customThe crude product was purified by silica gel chromatography
- washeluting with EtOAc:hexane (10:90 to 25:75)
出典と根拠
- ORDレコード
- ord-f16887e966bb40ceb8b064a9668b782d
- 出典データセット
- uspto-grants-2000_04
- 特許番号
- US06046355
反応ノート
読み込み中…