Potassium Acetate → Benzenemethanol, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 1-acetate

HRID 1004438

反応式

HRID 1004438 の反応式
Cl[CH2:2][C:3]1[CH:8]=[C:7]([C:9]([CH3:12])([CH3:11])[CH3:10])[C:6]([OH:13])=[C:5]([C:14]([CH3:17])([CH3:16])[CH3:15])[CH:4]=1.[C:18]([O-:21])(=[O:20])[CH3:19].[K+]>CC(C)=O>[C:18]([O:21][CH2:2][C:3]1[CH:8]=[C:7]([C:9]([CH3:12])([CH3:11])[CH3:10])[C:6]([OH:13])=[C:5]([C:14]([CH3:17])([CH3:16])[CH3:15])[CH:4]=1)(=[O:20])[CH3:19]

参加物

4

反応物 2

HCID 517044Potassium AcetateHCID 123786012,6-Di-tert-butyl-4-(chloromethyl)phenol

生成物 1

HCID 84404Benzenemethanol, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 1-acetate収率 45%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

反応条件

温度
20 °C

実験手順

A mixture of 4-chloromethyl-2,6-di-t-butylphenol (2.55 g) and potassium acetate (0.98 g) in acetone (30 mL) was stirred at 20° C. for 24 hours. After evaporation of the solvent the residue was partioned between water and n-hexane. The hexane extract was concentrated and the residue slurried in n-hexane (6 mL) at about 0° C. The crystals were collected via filtration and dried to give 1.54 g, 45% yield, of the title compound.

後処理

  1. customAfter evaporation of the solvent the residue
  2. extractionThe hexane extract
  3. concentrationwas concentrated
  4. customslurried in n-hexane (6 mL) at about 0° C
  5. filtrationThe crystals were collected via filtration
  6. customdried
  7. customto give 1.54 g, 45% yield

出典と根拠

ORDレコード
ord-c9941dd45f3945949a83a9d18e02784d
出典データセット
uspto-grants-2000_04
特許番号
US06048995

関連ノート

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