2-Methoxy-3-nitro-5-ethyl-6-methylpyridine → 2-Methoxy-3-amino-5-ethyl-6-methylpyridine
反応式
[CH3:1][O:2][C:3]1[C:8]([N+:9]([O-])=O)=[CH:7][C:6]([CH2:12][CH3:13])=[C:5]([CH3:14])[N:4]=1>CO.O1CCCC1.[Pd]>[CH3:1][O:2][C:3]1[C:8]([NH2:9])=[CH:7][C:6]([CH2:12][CH3:13])=[C:5]([CH3:14])[N:4]=1参加物
5
実験手順
A solution of 2-methoxy-3-nitro-5-ethyl-6-methylpyridine (535 mg, 2.72 mmol) in methanol (8 mL) and tetrahydrofuran (8 mL) containing 5% palladium on carbon (83 mg) was hydrogenated at atmospheric pressure for 5 hours. The catalyst was filtered off the solvent evaporated to yield 436 mg (98%) of oily product.
後処理
- filtrationThe catalyst was filtered off the solvent
- customevaporated
出典と根拠
- ORDレコード
- ord-43607c74710f483782df876a5943b4f2
- 出典データセット
- uspto-grants-1994_05
- 特許番号
- US05308854
反応ノート
読み込み中…