Butylamine → HCID 19025862、化合物
反応式
I[CH2:2][CH2:3][CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[OH:5].[CH2:12]([NH2:16])[CH2:13][CH2:14][CH3:15]>C1COCC1>[CH2:12]([NH:16][CH2:2][CH2:3][CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[OH:5])[CH2:13][CH2:14][CH3:15]参加物
4
実験手順
(Compound 15) (12.5 g) was treated with butylamine (40 ml) in THF (75 ml) at RT for 4 h. The mixture evaporated and the residue extracted with OH- /ether. The ether phase washed with H2O and saturated NaCl-solution, dried (MgSO4) and evaporated giving 6.2 g of 3-butylamino-1-phenyl-1-propanol (compound 16). Identified by 1H NMR.
後処理
- customThe mixture evaporated
- extractionthe residue extracted with OH- /ether
- washThe ether phase washed with H2O and saturated NaCl-solution
- dry with materialdried (MgSO4)
- customevaporated
出典と根拠
- ORDレコード
- ord-8a22d5906bd14ccd97b3f221b9a30ca7
- 出典データセット
- uspto-grants-1994_05
- 特許番号
- US05310756
反応ノート
読み込み中…