HCID 24829226、化合物 → 3-(6-Methoxynaphthalen-2-yl)aniline
反応式
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([N+:19]([O-])=O)[CH:14]=3)[CH:9]=2)[CH:4]=1>C1COCC1.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C:13]1[CH:14]=[C:15]([NH2:19])[CH:16]=[CH:17][CH:18]=1)[CH:7]=[CH:6]2参加物
4
実験手順
To a solution of 2-methoxy-6-(3-nitrophenyl)naphthalene (200 mg, 0.71 mmol, 1 eq) in 100 ml of dry THF, Pd/C is added, and the mixture is stirred over night at RT under a hydrogen atmosphere. After filtration over Celite and purification by means of preparative thin-layer chromatograph, the product is obtained in a yield of 20% (36 mg).
後処理
- filtrationAfter filtration
- customover Celite and purification by means of preparative thin-layer chromatograph
- customthe product is obtained in a yield of 20% (36 mg)
出典と根拠
- ORDレコード
- ord-81d3a3f1c3484e06afbb198bbe71142f
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08546392B2
反応ノート
読み込み中…