Tetrahydrofuran → 4-Methyl-N-[5-methyl-2-(7H-pyrrolo[2,3-d]pyrimidine-4-carbonyl)-pyridin-3-yl]-3-trifluoromethyl-benzenesulfonamide

反応式

C([C:3]1[C:8]([NH:9][S:10]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[C:15]([C:20]([F:23])([F:22])[F:21])[CH:14]=2)(=[O:12])=[O:11])=[CH:7][C:6]([CH3:24])=[CH:5][N:4]=1)#N.[H-].[Na+].I[C:28]1[C:29]2[CH:36]=[CH:35][NH:34][C:30]=2[N:31]=[CH:32][N:33]=1.C1C[O:40][CH2:39]C1>C1([Mg]Cl)C=CC=CC=1.C([Mg]Cl)(C)C>[CH3:19][C:16]1[CH:17]=[CH:18][C:13]([S:10]([NH:9][C:8]2[C:3]([C:39]([C:28]3[C:29]4[CH:36]=[CH:35][NH:34][C:30]=4[N:31]=[CH:32][N:33]=3)=[O:40])=[N:4][CH:5]=[C:6]([CH3:24])[CH:7]=2)(=[O:12])=[O:11])=[CH:14][C:15]=1[C:20]([F:21])([F:23])[F:22]