Diisopropylethylamine → tert-butyl 1-((2R)-3-(benzyloxy)-1-(2-methyl-1-oxo-4-phenyl-2,8-diazaspiro[4.6]undecan-8-yl)-1-oxopropan-2-ylamino)-2-methyl-1-oxopropan-2-ylcarbamate

反応式

[CH3:1][N:2]1[CH2:6][CH:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:4]2([CH2:18][CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)[C:3]1=[O:19].[CH2:20]([O:27][CH2:28][C@@H:29]([NH:33][C:34](=[O:46])[C:35]([NH:38][C:39]([O:41][C:42]([CH3:45])([CH3:44])[CH3:43])=[O:40])([CH3:37])[CH3:36])[C:30](O)=[O:31])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.CCN(C(C)C)C(C)C.C(P1(=O)OP(CCC)(=O)OP(CCC)(=O)O1)CC>CC#N.O>[CH2:20]([O:27][CH2:28][C@@H:29]([NH:33][C:34](=[O:46])[C:35]([NH:38][C:39](=[O:40])[O:41][C:42]([CH3:45])([CH3:44])[CH3:43])([CH3:37])[CH3:36])[C:30]([N:15]1[CH2:16][CH2:17][CH2:18][C:4]2([C:3](=[O:19])[N:2]([CH3:1])[CH2:6][CH:5]2[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH2:13][CH2:14]1)=[O:31])[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1